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. 2015 Aug 28;5:13519. doi: 10.1038/srep13519

Figure 3. GADD34 -deficient mice developed NASH by aging.

Figure 3

(a) Concentration of AST and ALT in serum from WT and GADD34-deficient young (3–4M) and aged (10M and >17M) mice were measured by ELISA Kit. Data shown are the mean ratio ± SEM. (n = 6, *p < 0.05, **p < 0.01). (b) Sections of the livers of 17 M old male WT (upper) and GADD34 -deficient (lower) mice were stained with H&E and Masson’s Trichrome. Scale bars represent 100 μm. (c) Frozen sections of 17 M old male WT (left) and GADD34 -deficient (right) mice liver were stained with anti-α-SMA-PE (Red), anti-GR-1-FITC (Green) and anti-CD4-APC (White).