Skip to main content
. 2015 Aug 28;5:13548. doi: 10.1038/srep13548

Figure 5. Predicted contribution to biotin production in gut microbiota.

Figure 5

(a) Components of pathways from pimelate to biotin. The black arrow indicates the step with a significant difference between the two groups. (b) Gene expression with a significant difference between the two groups. RPKM-normalized reads are shown as boxes that denote the interquartile range between the first and third quartiles, and the line within denotes the median (n = 6). P-values were calculated using the Mann–Whitney U test. *P < 0.05. (c) In vitro assay of biotin synthesis. Each strain was cultivated for 16 h in GAM broth with or without pimelate (10 mg/ml). Data are shown as the mean ± SD (n = 3). P-values were calculated using Student’s t-test. **P < 0.01.