Table 1. Microbiota profiles in fecal samples of HGM mice.
| Species | Median percent of total reads (interquartile range) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Day 0 |
Day 13 |
|||||||
| HGM group | BB536-HGM group | HGM group | BB536-HGM group | |||||
| R. obeum | 24.06 | (23.28–24.87) | 27.36 | (23.32–28.27) | 23.08 | (22–25.28) | 23.68 | (22.97–34.50) |
| B. caccae | 20.85 | (18.07–21.5) | 20.89 | (19.99–22.37) | 19.82 | (19.7–20.51) | 22.13 | (18.23–24.36) |
| B. vulgatus | 12.77 | (12.6–14.56) | 12.24 | (10.13–13.39) | 17.14 | (15.73–18.53) | 13.66 | (12.29–14.24)* |
| B. cellulosilyticus | 13.95 | (13.37–14.96) | 13.63 | (12.46–14.64) | 14.13 | (12.82–15.46) | 12.80 | (11.80–14.14) |
| B. thetaiotaomicron | 10.63 | (9.95–11.7) | 10.71 | (10.63–11.18) | 14.11 | (12.83–15.64)# | 13.06 | (9.89–14.17) |
| C. scindens | 4.25 | (3.68–4.97) | 5.18 | (3.84–7.35) | 4.08 | (3.67–4.98) | 4.15 | (3.66–4.94) |
| R. torques | 3.03 | (2.34–4.06) | 2.05 | (1.38–2.4)* | 3.05 | (2.54–3.54) | 2.88 | (2.61–3.13)# |
| B. ovatus | 4.16 | (4.03–5.07) | 3.78 | (3.50–4.28) | 0.25 | (0.18–0.30)# | 0.15 | (0.13–0.18)# |
| E. rectale | 1.92 | (1.39–2.18) | 1.96 | (1.87–2.52) | 1.01 | (0.84–1.03)# | 1.17 | (1.09–1.27)#,* |
| B. uniformis | 1.69 | (1.53–1.97) | 1.79 | (1.43–1.90) | 1.32 | (1.28–1.35) | 1.31 | (1.14–1.52)# |
| P. distasonis | 0.54 | (0.35–0.78) | 0.40 | (0.31–0.61) | 0.50 | (0.34–0.68) | 0.61 | (0.45–0.80) |
| F. prausnitzii | 0.51 | (0.50–0.56) | 0.51 | (0.38–0.53) | 0.45 | (0.40–0.52) | 0.46 | (0.44–0.51) |
| B. longum | 0.06 | (0.05–0.06) | 0.07 | (0.05–0.08) | 0.06 | (0.02–0.08) | 0.63 | (0.52–0.69)#,** |
| D. longicatena | 0.02 | (0–0.04) | 0.02 | (0.02–0.04) | 0.04 | (0.02–0.05) | 0.05 | (0.02–0.06) |
| C. spiroforme | 0.01 | (0–0.02) | 0 | (0–0.05) | 0 | (0–0) | 0 | (0–0) |
| C. aerofaciens | 0 | (0–0) | 0 | (0–0) | 0 | (0–0) | 0 | (0–0) |
Intra- and inter-group differences were analyzed using the Wilcoxon matched-pair signed-rank test and the Mann–Whitney U test, respectively. #P < 0.05 for significant intra-group differences from baseline (day 0). *P < 0.05; **P < 0.01 for significant inter-group differences compared to the HGM group.