Table 4. ICCs, average pair CVs, and correlation coefficients (r) using standardized values for 61 miRNAs measured in 80 participants one year apart.
Expressed at detectable levels in > 50% of samples | Expressed at detectable levels in ≤ 50% of samples | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Target meets established criteria | miRNA | ICC | Avg CV | Max CV | Polychoric r | % Detected | Target meets established criteria | miRNA | ICC | Avg CV | Max CV | Polychoric r | % Detected |
Yes | hsa-miR-191-5p | 0.5 | 5.6 | 39.4 | 0.59 | 100% | Yes | hsa-miR-145-3p | 0.6 | 2.4 | 10.7 | 0.59 | 2% |
Yes | hsa-miR-29c-3p | 0.5 | 8.2 | 29.7 | 0.47 | 100% | Yes | hsa-miR-130b-5p | 0.6 | 2.4 | 10.7 | 0.57 | 1% |
Yes | hsa-miR-17-5p | 0.4 | 7.6 | 33.0 | 0.45 | 99% | Yes | hsa-miR-199a-5p | 0.5 | 2.5 | 10.7 | 0.53 | 2% |
Yes | hsa-miR-133a | 0.4 | 6.4 | 29.3 | 0.38 | 59% | Yes | hsa-miR-29c-5p | 0.5 | 2.6 | 10.7 | 0.51 | 3% |
Yes | hsa-let-7d-5p | 0.4 | 3.7 | 16.9 | 0.39 | 75% | Yes | hsa-let-7d-3p | 0.5 | 2.6 | 12.4 | 0.46 | 1% |
Yes | hsa-miR-26a-5p | 0.4 | 7.2 | 21.6 | 0.47 | 99% | Yes | hsa-miR-424-3p | 0.5 | 2.7 | 21.2 | 0.54 | 3% |
Yes | hsa-miR-375 | 0.4 | 4.8 | 17.1 | 0.47 | 99% | No | hsa-miR-191-3p | 0.3 | 2.9 | 27.5 | 0.43 | 5% |
Yes | hsa-miR-320a | 0.4 | 5.4 | 18.6 | 0.38 | 100% | No | hsa-miR-10a-5p | 0.3 | 3.1 | 15.3 | 0.36 | 15% |
Yes | hsa-miR-130b-3p | 0.4 | 5.0 | 18.3 | 0.33 | 73% | No | hsa-miR-26b-3p | 0.3 | 3.5 | 12.8 | 0.33 | 16% |
Yes | hsa-miR-27b-3p | 0.4 | 6.1 | 44.4 | 0.46 | 100% | No | hsa-miR-133b | 0.3 | 3.0 | 34.8 | 0.44 | 4% |
No | hsa-miR-126-5p | 0.3 | 12.8 | 69.0 | 0.36 | 99% | No | hsa-let-7e-5p | 0.2 | 3.7 | 23.3 | 0.34 | 14% |
No | hsa-miR-222-3p | 0.3 | 4.2 | 54.5 | 0.48 | 98% | No | hsa-miR-22-3p | 0.2 | 3.6 | 19.5 | 0.23 | 24% |
No | hsa-miR-361-5p | 0.3 | 4.7 | 17.7 | 0.31 | 68% | No | hsa-miR-142-5p | 0.2 | 3.2 | 10.9 | 0.20 | 28% |
No | hsa-miR-21-5p | 0.3 | 7.0 | 29.8 | 0.35 | 99% | No | hsa-miR-151a-5p | 0.1 | 5.5 | 98.9 | 0.27 | 34% |
No | hsa-miR-126-3p | 0.3 | 4.3 | 19.8 | 0.32 | 100% | No | hsa-miR-193b-3p | 0.1 | 5.8 | 17.5 | 0.12 | 48% |
No | hsa-miR-26b-5p | 0.3 | 7.3 | 21.8 | 0.31 | 97% | — | hsa-miR-1 | NC | NC | NC | NC | 0% |
No | hsa-miR-409-3p | 0.3 | 6.2 | 42.9 | 0.62 | 99% | — | hsa-miR-155-5p | NC | NC | NC | NC | 0% |
No | hsa-miR-29b-3p | 0.3 | 6.8 | 28.2 | 0.36 | 100% | — | hsa-miR-23b-3p | NC | NC | NC | NC | 0% |
No | hsa-miR-210 | 0.3 | 8.6 | 24.9 | 0.28 | 84% | — | hsa-miR-23b-5p | NC | NC | NC | NC | 0% |
No | hsa-miR-20b-5p | 0.3 | 4.8 | 23.3 | 0.33 | 100% | — | hsa-miR-424-5p | NC | NC | NC | NC | 0% |
No | hsa-miR-140-3p | 0.2 | 4.7 | 14.8 | 0.27 | 91% | |||||||
No | hsa-miR-130a-3p | 0.2 | 4.3 | 29.5 | 0.34 | 99% | |||||||
No | hsa-miR-185-5p | 0.2 | 4.7 | 15.6 | 0.20 | 97% | |||||||
No | hsa-miR-223-5p | 0.2 | 6.8 | 122.1 | 0.33 | 96% | |||||||
No | hsa-miR-29a-3p | 0.2 | 4.5 | 16.7 | 0.17 | 98% | |||||||
No | hsa-miR-25-3p | 0.2 | 10.7 | 64.4 | 0.18 | 100% | |||||||
No | hsa-miR-145-5p | 0.2 | 4.9 | 14.7 | 0.16 | 76% | |||||||
No | hsa-miR-199a-3p | 0.2 | 4.0 | 13.2 | 0.28 | 100% | |||||||
No | hsa-miR-30c-5p | 0.2 | 7.3 | 47.2 | 0.19 | 100% | |||||||
No | hsa-miR-92a-3p | 0.2 | 9.2 | 37.9 | 0.17 | 100% | |||||||
No | hsa-miR-106b-5p | 0.1 | 5.5 | 25.8 | 0.15 | 100% | |||||||
No | hsa-miR-151a-3p | 0.1 | 5.6 | 36.5 | 0.17 | 78% | |||||||
No | hsa-miR-221-3p | 0.1 | 4.8 | 40.6 | 0.22 | 99% | |||||||
No | hsa-miR-93-5p | 0.1 | 5.5 | 20.4 | 0.14 | 100% | |||||||
No | hsa-miR-93-3p | 0.1 | 5.9 | 43.9 | 0.15 | 82% | |||||||
No | hsa-miR-122-5p | 0.1 | 7.2 | 24.8 | 0.21 | 51% | |||||||
No | hsa-miR-22-5p | 0.1 | 7.2 | 100.0 | 0.17 | 79% | |||||||
No | hsa-miR-30b-5p | 0.1 | 7.0 | 72.6 | 0.15 | 100% | |||||||
No | hsa-miR-27a-3p | <0.1 | 5.4 | 23.5 | -0.03 | 100% | |||||||
No | hsa-miR-320b | <0.1 | 15.8 | 85.9 | 0.38 | 99% | |||||||
No | hsa-miR-30e-3p | <0.1 | 17.3 | 114.2 | 0.25 | 99% |
Bold indicates acceptable results and italics indicates unacceptable results, NC = not calculated.