. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2015 Aug 11;5(1):85–101. doi: 10.1002/wdev.202

Table 1.

	Link type	Composition	Appearance in mouse	Associated proteins /regulators	Associated human deafness loci
Permanent	Tip	CDH23 PCDH15	E17.5	myosin VIIa, SANS, harmonin TMHS/LHFPL5	USH1^*
Permanent	Horizontal top connectors	stereocilin	P9	None reported	DFNB16
Transient	Tansient lateral links / Shaft connectors	CDH23 PCDH15 / PTPRQ?	E17.5	myosin VIIa, SANS, harmonin	USH1^*
	Kinociliary	CDH23 PCDH15-CD2	E17.5	myosin VIIa, SANS, harmonin	USH1^*
	Ankle	GPR98 VLGR1 usherin	P0	PDZD7, whirlin	USH2^*

This link type is also associated with additional forms of nonsydromic hearing loss. See http://hereditaryhearingloss.org for a comprehensive list.