Figure 2.

Glomeruli from adults are larger and have more variable size than glomeruli from children. A and B show representative images of average glomeruli from children and adults, respectively, using periodic acid–Schiff staining. (C) IGV values in 16 Caucasian-American men and boys. Each circle represents one glomerulus, and each column represents one subject with 30 glomeruli per subject; Ch1–Ch4 represent four young children (gray), and A1–A12 represent 12 adults (white) ranked by median IGV. (D) Aggregated IGV differences between children and adults. (E) Difference in IGV variance per subject between glomeruli from children and adults. (F) IGV distributions in children (solid line with gray area) and adults (dotted line). Bars represent median values with IQR. Scale bars, 50 μm. **P<0.01; ****P<0.001.