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. 2015 Jan 2;26(9):2172–2182. doi: 10.1681/ASN.2014070664

Figure 2.

Figure 2.

Peripheral and organ neutrophil analysis in THP+/+ and THP−/− mice. (A–D) Flow cytometry analysis of neutrophils in the kidney (A and B) and liver (C and D) from both strains of mice. A and C show representative scatter plots of CD45+ cells in the kidney and liver, respectively, gated for CD11b and Ly6G. Quantitation of neutrophils (defined as CD45+, CD11b+, Ly6G+) in the kidney and liver are shown in B and D, respectively (n=5 per group). Asterisks denote statistical significance between THP+/+ and THP−/− (P<0.05). (E and F) Bar graphs are means±SEM of peripheral white blood cell count and its subtypes from THP+/+ and THP−/− mice (n=8 per group). E depicts cell concentration in blood, whereas F shows the percentage of each cell type within the total white blood cell count. A significant increase in neutrophils is noted in THP−/− versus THP+/+ (*P<0.05). Neut, neutrophil; WBC, white blood cell count; NE, neutrophil; LY, lymphocyte; MO, monocyte; EO, eosinophil; BA, basophil.