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. 2015 Mar 19;26(9):2222–2229. doi: 10.1681/ASN.2014070726

Table 3.

Univariate HRs of graft loss and death among HIV+ recipients

Demographics Risk of Graft Loss Risk of Death
HR (95% CI) P Value HR (95% CI) P Value
Recipient characteristics
 Age≥50 yr 1.16 (0.83 to 1.62) 0.38 2.05 (1.36 to 3.09) <0.001
 Male sex 0.91 (0.61 to 1.35) 0.64 0.88 (0.53 to 1.46) 0.62
 African American race 1.34 (0.92 to 1.94) 0.13 0.78 (0.51 to 1.22) 0.28
 BMI (kg/m2)
  Normal weight Reference Reference
  Underweight 1.14 (0.36 to 3.62) 0.83 2.13 (0.66 to 6.92) 0.21
  Overweight 0.73 (0.49 to 1.09) 0.12 0.56 (0.32 to 0.96) 0.04
  Obese 0.79 (0.47 to 1.32) 0.37 0.60 (0.30 to 1.23) 0.31
 Peak PRA>80% 1.79 (1.01 to 3.16) 0.05 1.62 (0.78 to 3.36) 0.19
 HCV infection 2.41 (1.73 to 3.38) <0.001 2.85 (1.89 to 4.31) <0.001
 Antithymocyte globulin induction 0.94 (0.64 to 1.37) 0.74 1.14 (0.71 to 1.82) 0.59
 CNI maintenance regimen 0.60 (0.37 to 0.96) 0.03 0.61 (0.34 to 1.10) 0.10
 Acute rejection within 1 yr 1.56 (1.05 to 2.31) 0.03 0.62 (0.33 to 1.16) 0.14
 Maintenance steroids 1.15 (0.76 to 1.72) 0.51 1.14 (0.67 to 1.94) 0.63
Donor characteristics
 Age≥50 yr 1.02 (0.69 to 1.49) 0.93 1.09 (0.68 to 1.75) 0.73
 Race
Caucasian Reference Reference
African American 0.89 (0.60 to 1.34) 0.59 0.60 (0.34 to 1.05) 0.07
Other 1.24 (0.80 to 1.91) 0.33 1.10 (0.64 to 1.88) 0.90
 Living donor 0.45 (0.30 to 0.68) <0.001 0.49 (0.29 to 0.83) 0.01
 Expanded criteria donor 1.51 (0.90 to 2.54) 0.12 1.34 (0.73 to 2.57) 0.33
 Donor after cardiac death 0.94 (0.51 to 1.73) 0.83 0.78 (0.34 to 1.79) 0.56
 CIT>10 ha 1.69 (1.01 to 2.82) 0.05 1.59 (0.82 to 3.11) 0.17
a

Among deceased donor transplants only.