Table 3.
Univariate HRs of graft loss and death among HIV+ recipients
| Demographics | Risk of Graft Loss | Risk of Death | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Recipient characteristics | ||||
| Age≥50 yr | 1.16 (0.83 to 1.62) | 0.38 | 2.05 (1.36 to 3.09) | <0.001 |
| Male sex | 0.91 (0.61 to 1.35) | 0.64 | 0.88 (0.53 to 1.46) | 0.62 |
| African American race | 1.34 (0.92 to 1.94) | 0.13 | 0.78 (0.51 to 1.22) | 0.28 |
| BMI (kg/m2) | ||||
| Normal weight | Reference | Reference | ||
| Underweight | 1.14 (0.36 to 3.62) | 0.83 | 2.13 (0.66 to 6.92) | 0.21 |
| Overweight | 0.73 (0.49 to 1.09) | 0.12 | 0.56 (0.32 to 0.96) | 0.04 |
| Obese | 0.79 (0.47 to 1.32) | 0.37 | 0.60 (0.30 to 1.23) | 0.31 |
| Peak PRA>80% | 1.79 (1.01 to 3.16) | 0.05 | 1.62 (0.78 to 3.36) | 0.19 |
| HCV infection | 2.41 (1.73 to 3.38) | <0.001 | 2.85 (1.89 to 4.31) | <0.001 |
| Antithymocyte globulin induction | 0.94 (0.64 to 1.37) | 0.74 | 1.14 (0.71 to 1.82) | 0.59 |
| CNI maintenance regimen | 0.60 (0.37 to 0.96) | 0.03 | 0.61 (0.34 to 1.10) | 0.10 |
| Acute rejection within 1 yr | 1.56 (1.05 to 2.31) | 0.03 | 0.62 (0.33 to 1.16) | 0.14 |
| Maintenance steroids | 1.15 (0.76 to 1.72) | 0.51 | 1.14 (0.67 to 1.94) | 0.63 |
| Donor characteristics | ||||
| Age≥50 yr | 1.02 (0.69 to 1.49) | 0.93 | 1.09 (0.68 to 1.75) | 0.73 |
| Race | ||||
| Caucasian | Reference | Reference | ||
| African American | 0.89 (0.60 to 1.34) | 0.59 | 0.60 (0.34 to 1.05) | 0.07 |
| Other | 1.24 (0.80 to 1.91) | 0.33 | 1.10 (0.64 to 1.88) | 0.90 |
| Living donor | 0.45 (0.30 to 0.68) | <0.001 | 0.49 (0.29 to 0.83) | 0.01 |
| Expanded criteria donor | 1.51 (0.90 to 2.54) | 0.12 | 1.34 (0.73 to 2.57) | 0.33 |
| Donor after cardiac death | 0.94 (0.51 to 1.73) | 0.83 | 0.78 (0.34 to 1.79) | 0.56 |
| CIT>10 ha | 1.69 (1.01 to 2.82) | 0.05 | 1.59 (0.82 to 3.11) | 0.17 |
Among deceased donor transplants only.