Table 1.
First MRS assessment | Second MRS assessment | ||||||
---|---|---|---|---|---|---|---|
Number of patients | Age (years) | Disease duration (months) | SARA scores | Disease duration (months) | SARA scores | Interval in between 2 MRS assessments (months) | |
p # | 0.03 | 0.326 | 0.195 | 0.736 | 0.114 | 0.680 | |
SCA2 | 5 | 60.6 ± 11.1* | 3.7 ± 3.03 | 8.4 ± 3.13 | 43.0 ± 15.47 | 17.13 ± 7.1 | 38.63 ± 13.21 |
SCA3 | 18 | 46.3 ± 10.0* | 6.14 ± 3.96 | 10.97 ± 6.28 | 49.91 ± 23.82 | 15.28 ± 5.23 | 43.78 ± 21.74 |
SCA6 | 3 | 59.0 ± 13.9 | 6.83 ± 2.36 | 12.5 ± 2.65 | 42.25 ± 15.2 | 19.0 ± 1.41 | 34.5 ± 17.68 |
MSA-C | 12 | 60.6 ± 6.1* | 4.25 ± 2.20 | 15.29 ± 6.71 | 38.7 ± 12.33 | 22.35 ± 7.02 | 34.3 ± 12.82 |
HC | 44 | 51.1 ± 17.9 | -- | -- | -- |
SCA2: Spinocerebellar ataxia type 2; SCA3: Spinocerebellar ataxia type 3; SCA6: Spinocerebellar ataxia type 6; MSA: Multiple system atrophy- cerebellar type; HC: Healthy controls.
*The patients with SCA 3 were significantly younger than those with SCA2 (p = 0.014) or MSA-C (p = 0.001).
#Kruskal-Wallis test.