Table 3.
The differences in MRS metabolites between patient groups at the 1 st MRS assessment
| Disease | SCA3 * | SCA6 * | MSA-C * | ||
|---|---|---|---|---|---|
| Cerebellar hemispheres | NAA/Cr | SCA2 | 0.000 | 0.004 | 0.155 |
| SCA3 | - | 0.356 | 0.000 | ||
| SCA6 | - | - | 0.000 | ||
| Cho/Cr | SCA2 | 0.010 | 0.039 | 0.035 | |
| SCA3 | - | 0.985 | 0.000 | ||
| SCA6 | - | - | 0.002 | ||
| NAA/Cho | SCA2 | 0.236 | 0.606 | 0.743 | |
| SCA3 | - | 0.356 | 0.018 | ||
| SCA6 | - | - | 0.401 | ||
| Vermis | NAA/Cr | SCA2 | 0.037 | 0.297 | 0.013 |
| SCA3 | - | 0.487 | 0.000 | ||
| SCA6 | - | - | 0.024 | ||
| Cho/Cr | SCA2 | 0.256 | 0.180 | 0.064 | |
| SCA3 | - | 0.252 | 0.001 | ||
| SCA6 | - | - | 0.011 | ||
| NAA/Cho | SCA2 | 0.730 | 0.456 | 0.493 | |
| SCA3 | - | 0.158 | 0.092 | ||
| SCA6 | - | - | 0.665 |
SCA2: Spinocerebellar ataxia type 2; SCA3: Spinocerebellar ataxia type 3; SCA6: Spinocerebellar ataxia type 6; MSA-C: Multiple system atrophy- cerebellar type.
*Mann–Whitney test, p-value.