Table 4.
The differences in MRS metabolites between patient groups at 2 nd MRS assessment
| Disease | SCA3* | SCA6* | MSA-C* | ||
|---|---|---|---|---|---|
| Cerebellar hemispheres | NAA/Cr | SCA2 | 0.001 | 0.014 | 0.017 |
| SCA3 | - | 0.538 | 0.000 | ||
| SCA6 | - | - | 0.022 | ||
| Cho/Cr | SCA2 | 0.197 | 0.393 | 0.055 | |
| SCA3 | - | 0.979 | 0.001 | ||
| SCA6 | - | - | 0.067 | ||
| NAA/Cho | SCA2 | 0.026 | 0.089 | 0.617 | |
| SCA3 | - | 0.456 | 0.077 | ||
| SCA6 | - | - | 0.202 | ||
| Vermis | NAA/Cr | SCA2 | 0.064 | 0.355 | 0.356 |
| SCA3 | - | 0.526 | 0.000 | ||
| SCA6 | - | - | 0.085 | ||
| Cho/Cr | SCA2 | 0.017 | 0.064 | 0.480 | |
| SCA3 | - | 0.880 | 0.003 | ||
| SCA6 | - | - | 0.133 | ||
| NAA/Cho | SCA2 | 0.484 | 0.165 | 0.777 | |
| SCA3 | - | 0.233 | 0.202 | ||
| SCA6 | - | - | 0.390 |
SCA2: Spinocerebellar ataxia type 2; SCA3: Spinocerebellar ataxia type 3; SCA6: Spinocerebellar ataxia type 6; MSA-C: Multiple system atrophy-cerebellar type.
*Mann–Whitney test, p value.