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A discrete region of the CaSR cytoplasmic tail is required for enhanced neurite growth.
(A) Sholl plots of E18 SCG neurite arbors after 24 h in NGF-free medium containing 2.3 mM [Ca2+]o plus 50 μM Boc-D-FMK after transfection with either pcDNA3.1, pFLCaSR or pG907stopCaSR (data from 223 to 259 neurons per condition). (B) Neurons transfected with either pcDNA3.1, pFLCaSR or pA877stopCaSR (data from 182 to 210 neurons per condition).
