TABLE 4.
Allele | G Groupingb | RV144 | Northeast Thais (7) | Southern China (Han) (16) | Taiwan (17) | Mongolia (Khalkha) (18) | Vietnam (19) | Japan (20) | South Korea (21) | India (Delhi) (22) | EUR (23) | AFA (23) | API (23) | HIS (23) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2N=900 | 2N=800 | 2N=528 | 2N=728 | 2N=200 | 2N=340 | 2N=742 | 2N=970 | 2N=188 | 2N=12792 | 2N=3734 | 2N=2454 | 2N=2936 | ||
DRB1*01:01 | DRB1*01:01:01G | 0.003 | 0.001c | 0.004 | 0.003 | 0.025 | 0.065 | 0.068 | 0.005 | 0.091 | 0.026 | 0.027 | 0.039 | |
DRB1*03:01 | DRB1*03:01:01G | 0.051 | 0.061 | 0.066 | 0.067 | 0.090 | 0.047 | 0.029 | 0.122 | 0.129 | 0.071 | 0.054 | 0.073 | |
DRB1*04:03 | 0.017 | 0.016 | 0.044 | 0.012 | 0.025 | 0.021 | 0.040 | 0.035 | 0.047 | 0.006 | 0.002 | 0.035 | 0.019 | |
DRB1*04:04 | 0.004 | 0.003 | 0.006 | 0.005 | 0.003 | 0.001 | 0.022 | 0.026 | 0.036 | 0.007 | 0.009 | 0.055 | ||
DRB1*04:05 | 0.052 | 0.059 | 0.042 | 0.059 | 0.050 | 0.038 | 0.115 | 0.092 | 0.005 | 0.004 | 0.010 | 0.058 | 0.019 | |
DRB1*04:06 | DRB1*04:06:01G | 0.010 | 0.004 | 0.021 | 0.029 | 0.006 | 0.035 | 0.041 | 0.005 | 0.001 | 0.021 | 0.002 | ||
DRB1*04:10 | 0.001 | 0.002 | 0.018 | 0.010 | 0.001 | 0.004 | 0.005 | |||||||
DRB1*04:87 | 0.001 | |||||||||||||
DRB1*07:01 | DRB1*07:01:01G | 0.104 | 0.059c | 0.057 | 0.045 | 0.120 | 0.076 | 0.003 | 0.072 | 0.175 | 0.138 | 0.098 | 0.082 | 0.105 |
DRB1*08:03/19 | 0.015 | 0.014c | 0.059 | 0.098 | 0.025 | 0.041 | 0.081 | 0.080 | 0.001 | 0.052 | 0.001 | |||
DRB1*09:01 | DRB1*09:01:02G | 0.101 | 0.071c | 0.144 | 0.194 | 0.095 | 0.097 | 0.124 | 0.092 | 0.011 | 0.008 | 0.032 | 0.102 | 0.010 |
DRB1*10:01 | 0.022 | 0.024 | 0.011 | 0.011 | 0.040 | 0.056 | 0.009 | 0.017 | 0.048 | 0.008 | 0.019 | 0.031 | 0.015 | |
DRB1*11:01 | DRB1*11:01:01G | 0.026 | 0.026 | 0.070 | 0.099 | 0.065 | 0.015 | 0.034 | 0.044 | 0.059 | 0.057 | 0.087 | 0.051 | 0.042 |
DRB1*11:06 | DRB1*11:06:01G | 0.018 | 0.026 | 0.005 | 0.001 | 0.003 | ||||||||
DRB1*12:01 | DRB1*12:01:01G | 0.006 | 0.028 | 0.037 | 0.025 | 0.009 | 0.038 | 0.033 | 0.005 | 0.015 | 0.040 | 0.029 | 0.012 | |
DRB1*12:02 | 0.167 | 0.134 | 0.133 | 0.098 | 0.045 | 0.353 | 0.015 | 0.033 | 0.011 | 0.000 | 0.003 | 0.074 | 0.001 | |
DRB1*13:01 | DRB1*13:01:01G | 0.003 | 0.004 | 0.009 | 0.001 | 0.035 | 0.006 | 0.007 | 0.009 | 0.059 | 0.063 | 0.056 | 0.024 | 0.042 |
DRB1*13:02 | 0.010 | 0.010 | 0.028 | 0.026 | 0.035 | 0.018 | 0.077 | 0.087 | 0.059 | 0.040 | 0.064 | 0.036 | 0.039 | |
DRB1*13:03 | 0.001 | 0.019 | 0.018 | 0.016 | 0.010 | 0.037 | 0.015 | |||||||
DRB1*13:12 | 0.011 | 0.008 | 0.007 | 0.004 | ||||||||||
DRB1*14:01 | DRB1*14:01:01G | 0.030 | 0.034 | 0.017 | 0.037 | 0.045 | 0.032 | 0.042 | 0.030 | 0.027 | 0.025 | 0.021 | 0.024 | 0.014 |
DRB1*14:04 | 0.037 | 0.028 | 0.002 | 0.003 | 0.018 | 0.074 | 0.020 | |||||||
DRB1*14:05 | 0.008 | 0.004 | 0.019 | 0.008 | 0.012 | 0.011 | 0.035 | 0.018 | ||||||
DRB1*14:10 | 0.004 | 0.002 | ||||||||||||
DRB1*14:18 | 0.001 | 0.001 | 0.001 | |||||||||||
DRB1*14:22 | 0.002 | |||||||||||||
DRB1*15:01 | DRB1*15:01:01G | 0.086 | 0.078 | 0.108 | 0.091 | 0.060 | 0.038 | 0.085 | 0.074 | 0.059 | 0.144 | 0.029 | 0.079 | 0.067 |
DRB1*15:02 | 0.144 | 0.183 | 0.053 | 0.023 | 0.035 | 0.062 | 0.100 | 0.033 | 0.059 | 0.008 | 0.002 | 0.081 | 0.013 | |
DRB1*15:03 | DRB1*15:03:01G | 0.002 | 0.117 | 0.001 | 0.011 | |||||||||
DRB1*15:04 | 0.007 | 0.001 | ||||||||||||
DRB1*15:06 | 0.002 | 0.021 | 0.004 | |||||||||||
DRB1*16:02 | 0.050 | 0.075 | 0.053 | 0.025 | 0.005 | 0.018 | 0.009 | 0.006 | 0.011 | 0.001 | 0.015 | 0.020 | 0.021 |
AFA, African American; API, Asian American; EUR, European American; HIS, Hispanic American.
Bold values: Significant at a p-value threshold of 0.05.
Nomenclature used for alleles that were ambiguous for exon 2 by four-digit HLA typing.
Reported as two-digit allele.