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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Tissue Antigens. 2015 Feb;85(2):117–126. doi: 10.1111/tan.12507

TABLE 4.

Comparison of HLA-DRB1 allele frequencies between RV144 individuals and other populationsa

Allele G Groupingb RV144 Northeast Thais (7) Southern China (Han) (16) Taiwan (17) Mongolia (Khalkha) (18) Vietnam (19) Japan (20) South Korea (21) India (Delhi) (22) EUR (23) AFA (23) API (23) HIS (23)
2N=900 2N=800 2N=528 2N=728 2N=200 2N=340 2N=742 2N=970 2N=188 2N=12792 2N=3734 2N=2454 2N=2936
DRB1*01:01 DRB1*01:01:01G 0.003 0.001c 0.004 0.003 0.025 0.065 0.068 0.005 0.091 0.026 0.027 0.039
DRB1*03:01 DRB1*03:01:01G 0.051 0.061 0.066 0.067 0.090 0.047 0.029 0.122 0.129 0.071 0.054 0.073
DRB1*04:03 0.017 0.016 0.044 0.012 0.025 0.021 0.040 0.035 0.047 0.006 0.002 0.035 0.019
DRB1*04:04 0.004 0.003 0.006 0.005 0.003 0.001 0.022 0.026 0.036 0.007 0.009 0.055
DRB1*04:05 0.052 0.059 0.042 0.059 0.050 0.038 0.115 0.092 0.005 0.004 0.010 0.058 0.019
DRB1*04:06 DRB1*04:06:01G 0.010 0.004 0.021 0.029 0.006 0.035 0.041 0.005 0.001 0.021 0.002
DRB1*04:10 0.001 0.002 0.018 0.010 0.001 0.004 0.005
DRB1*04:87 0.001
DRB1*07:01 DRB1*07:01:01G 0.104 0.059c 0.057 0.045 0.120 0.076 0.003 0.072 0.175 0.138 0.098 0.082 0.105
DRB1*08:03/19 0.015 0.014c 0.059 0.098 0.025 0.041 0.081 0.080 0.001 0.052 0.001
DRB1*09:01 DRB1*09:01:02G 0.101 0.071c 0.144 0.194 0.095 0.097 0.124 0.092 0.011 0.008 0.032 0.102 0.010
DRB1*10:01 0.022 0.024 0.011 0.011 0.040 0.056 0.009 0.017 0.048 0.008 0.019 0.031 0.015
DRB1*11:01 DRB1*11:01:01G 0.026 0.026 0.070 0.099 0.065 0.015 0.034 0.044 0.059 0.057 0.087 0.051 0.042
DRB1*11:06 DRB1*11:06:01G 0.018 0.026 0.005 0.001 0.003
DRB1*12:01 DRB1*12:01:01G 0.006 0.028 0.037 0.025 0.009 0.038 0.033 0.005 0.015 0.040 0.029 0.012
DRB1*12:02 0.167 0.134 0.133 0.098 0.045 0.353 0.015 0.033 0.011 0.000 0.003 0.074 0.001
DRB1*13:01 DRB1*13:01:01G 0.003 0.004 0.009 0.001 0.035 0.006 0.007 0.009 0.059 0.063 0.056 0.024 0.042
DRB1*13:02 0.010 0.010 0.028 0.026 0.035 0.018 0.077 0.087 0.059 0.040 0.064 0.036 0.039
DRB1*13:03 0.001 0.019 0.018 0.016 0.010 0.037 0.015
DRB1*13:12 0.011 0.008 0.007 0.004
DRB1*14:01 DRB1*14:01:01G 0.030 0.034 0.017 0.037 0.045 0.032 0.042 0.030 0.027 0.025 0.021 0.024 0.014
DRB1*14:04 0.037 0.028 0.002 0.003 0.018 0.074 0.020
DRB1*14:05 0.008 0.004 0.019 0.008 0.012 0.011 0.035 0.018
DRB1*14:10 0.004 0.002
DRB1*14:18 0.001 0.001 0.001
DRB1*14:22 0.002
DRB1*15:01 DRB1*15:01:01G 0.086 0.078 0.108 0.091 0.060 0.038 0.085 0.074 0.059 0.144 0.029 0.079 0.067
DRB1*15:02 0.144 0.183 0.053 0.023 0.035 0.062 0.100 0.033 0.059 0.008 0.002 0.081 0.013
DRB1*15:03 DRB1*15:03:01G 0.002 0.117 0.001 0.011
DRB1*15:04 0.007 0.001
DRB1*15:06 0.002 0.021 0.004
DRB1*16:02 0.050 0.075 0.053 0.025 0.005 0.018 0.009 0.006 0.011 0.001 0.015 0.020 0.021

AFA, African American; API, Asian American; EUR, European American; HIS, Hispanic American.

a

Bold values: Significant at a p-value threshold of 0.05.

b

Nomenclature used for alleles that were ambiguous for exon 2 by four-digit HLA typing.

c

Reported as two-digit allele.