#	Searches	Results
1	exp Osteoarthritis, Knee/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed	11075
2	exp knee osteoarthritis/ use emez	16582
3	arthritis/ or osteoarthritis/	153312
4	exp Knee/	51979
5	exp Knee Joint/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed	43151
6	exp Knee Injuries/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed	15761
7	exp knee injury/ use emez	21986
8	exp knee meniscus/ use emez	5228
9	3 and (4 or 5 or 6 or 7 or 8)	14304
10	exp knee meniscus rupture/ use emez	3474
11	((osteoarthrit∗ or osteoarthro∗ or oa or degenerative or tear or injur∗) adj3 (knee∗ or menisc∗ or semilunar cartilage or superior tibiofibular∗ or femorotibia∗)).ti,ab.	38496
12	or/1–2,9–11	61166
13	exp Arthroscopy/	37349
14	exp knee arthroscopy/ use emez	4444
15	exp arthroscopic debridement/ use emez	416
16	exp Debridement/	36671
17	exp Curettage/	16239
18	(28nglish2828py∗ or debride∗ or curettage∗).ti,ab.	97624
19	or/13–18	132191
20	12 and 19	7475
21	exp Menisci, Tibial/su [Surgery]	4035
22	exp Menisci, Tibial/in [Injuries]	3042
23	exp meniscal surgery/ use emez	2308
24	or/20–23	13487
25	(Meta Analysis or Controlled Clinical Trial).pt.	214105
26	Meta-Analysis/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed or exp Technology Assessment, Biomedical/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed	52834
27	Meta Analysis/ use emez or Biomedical Technology Assessment/ use emez	91903
28	(meta analy∗ or metaanaly∗ or pooled analysis or (systematic∗ adj2 review∗) or published studies or published literature or medline or embase or data synthesis or data extraction or 29nglish29 or ((health technolog∗ or biomedical technolog∗) adj2 assess∗)).ti,ab.	397128
29	exp Randomized Controlled Trial/	726701
30	exp Random Allocation/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed or exp Double-Blind Method/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed or exp Control Groups/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed or exp Placebos/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed	338551
31	exp Randomization/ use emez or exp RANDOM SAMPLE/ use emez or Double Blind Procedure/ use emez or exp Triple Blind Procedure/ use emez or exp Control Group/ use emez or exp PLACEBO/ use emez	420313
32	(random∗ or RCT or placebo∗ or sham∗ or (control∗ adj2 clinical trial∗)).ti,ab.	2230045
33	or/25–32	3037891
34	24 and 33	1456
35	limit 34 to 29nglish language [Limit not valid in CDSR,ACP Journal Club,DARE,CCTR,CLCMR; records were retained]	1338
36	limit 35 to yr=“1995 –Current” [Limit not valid in DARE; records were retained]	1203
37	remove duplicates from 36	804