. 2015 Jun 4;36(9):982–991. doi: 10.1093/carcin/bgv082

Table 2.

Conditional logistic regression analysis of APE1 activity value in lung cancer patients and control subjects

Variable	No. of control subjects (%)	No. of case patients (%)	Adjusted^a OR (95% CI)
APE1 (per 211U decrease)^b,c	96 (100.0)	96 (100.0)	2.0 (1.3–3.1) P = 0.002
APE1 (by tertiles)^d			1.0 (referent)
>847 U	32 (33.3)	19 (19.8)	0.9 (0.3–2.2) P = 0.77
718–847 U	32 (33.3)	17 (17.7)	3.3 (1.4–8.1) P = 0.008
≤718 U	32 (33.3)	60 (62.5)	Trend test^d P = 0.004

^aConditional logistic regression for matched sets adjusted for smoking status (smoker, ex-smoker, never smoker).

^bAPE activity was measured as described in the Materials and methods and was first fitted in the conditional logistic regression model as a continuous variable and with adjustment for smoking status. The odds ratio for smoking that was obtained with this model, was: ex-smoker v never smoker: 3.4 (95% CI= 1.4–8.2); current smoker v never smoker: 2.6 (1.1–6.1).

^c211U represents 1 SD in the control group.

^dTertiles of the control subjects’ values. The upper tertile was chosen as the referent.