Table 2.
Top10 of the genes differently expressed in S. cerevisiae in single-culture (Sc) and mixed-culture (Mc) fermentations, at the three fermentation stages (24, 48 and 96 h)
| ORF | Gene | Function | Fold change Sc/Mc |
|---|---|---|---|
| 24 h | |||
| YCL025C | AGP1 | Low-affinity amino acid permease with broad substrate range | 13.4 |
| YDR508C | GNP1 | High-affinity glutamine permease | 8.1 |
| YOL086 W-A | Molecular function unknown | 5.7 | |
| YHR021 W-A | ECM12 | Putative protein of unknown function | 5.3 |
| YKL183C-A | Putative protein of unknown function | 5.1 | |
| YOR348C | PUT4 | Proline permease | 4.8 |
| YDR130C | FIN1 | Spindle pole body-related intermediate filament protein | 4.6 |
| YBL042C | FUI1 | High affinity uridine permease | 4.5 |
| YAL037C-A | Putative protein of unknown function | 4.4 | |
| YBL052C | SAS3 | Histone acetyltransferase activity | 4.0 |
| YHR044C | DOG1 | 2-deoxyglucose-6-phosphate phosphatase | −11.8 |
| YDR018C | Transferase activity, transferring acyl groups | −8.9 | |
| YPL258C | THI21 | Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis | −7.9 |
| YDL021 W | GPM2 | Molecular function unknown | −7.1 |
| YHR043C | DOG2 | 2-deoxyglucose-6-phosphate phosphatase | −6.7 |
| YCR020C | PET18 | Protein of unknown function | −6.1 |
| YLR176C | RFX1 | Major transcriptional repressor of DNA-damage-regulated genes | −6.1 |
| YHL048C-A | Putative protein of unknown function | −5.9 | |
| YOL055C | THI20 | Trifunctional enzyme of thiamine biosynthesis, degradation and salvage | −5.6 |
| YHR076 W | PTC7 | Type 2C serine/threonine protein phosphatase (PP2C) | −5.5 |
| 48 h | |||
| YLR142 W | PUT1 | Proline oxidase involved in utilization of proline as sole nitrogen source | 55.3 |
| YJR152 W | DAL5 | Allantoate permease | 52.7 |
| YKR039 W | GAP1 | General amino acid permease | 25.3 |
| YMR107 W | SPG4 | Molecular function unknown | 23.3 |
| YMR175 W | SIP18 | Phospholipid binding | 21.2 |
| YMR118C | Putative mitochondrial inner membrane protein of unknown function | 20.3 | |
| YPR194C | OPT2 | Oligopeptide transporter | 18.3 |
| YCR098C | GIT1 | Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate | 17.4 |
| YHL016C | DUR3 | Plasma membrane transporter for both urea and polyamines | 15.4 |
| YCL064C | CHA1 | Catabolic l-serine (l-threonine) deaminase | 13.8 |
| YMR095C | SNO1 | Protein of unconfirmed function; involved in pyridoxine metabolism; expression is induced during stationary phase | −14.2 |
| YCL026C-A | FRM2 | Type II nitroreductase, using NADH as reductant | −13.7 |
| YGL117 W | Putative protein of unknown function | −12.9 | |
| YBR092C | PHO3 | Acid phosphatase activity | −10.1 |
| YMR094 W | CTF13 | Subunit of the CBF3 complex | −9.9 |
| YML116 W | ATR1 | Multidrug efflux pump of the major facilitator superfamily | −8.2 |
| YML123C | PHO84 | High-affinity inorganic phosphate (Pi) transporter | −8.0 |
| YLR372 W | SUR4 | Elongase; involved in fatty acid and sphingolipid biosynthesis | −7.8 |
| YGL162 W | SUT1 | Transcription factor of the Zn(II)2Cys6 family; positively regulates genes involved in sterol uptake under anaerobic conditions | −7.2 |
| YBR249C | ARO4 | 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase | −6.9 |
| 96 h | |||
| YEL061C | CIN8 | Kinesin motor protein | 86.2 |
| YJL051 W | IRC8 | Bud tip localized protein of unknown function | 43.0 |
| YJL148 W | RPA34 | RNA polymerase I subunit A34.5 | 28.6 |
| YNL129 W | NRK1 | Nicotinamide riboside kinase | 27.6 |
| YLR265C | NEJ1 | Protein involved in regulation of non homologous end joining | 25.9 |
| YOR177C | MPC54 | Component of the meiotic outer plaque | 21.9 |
| YOR305 W | RRG7 | Protein of unknown function | 21.0 |
| YLR151C | PCD1 | 8-oxo-dGTP diphosphatase | 21.0 |
| YKL011C | CCE1 | Mitochondrial cruciform cutting endonuclease | 21.0 |
| YDR523C | SPS1 | Putative protein serine/threonine kinase | 19.5 |
| YBR194 W | AIM4 | Protein proposed to be associated with the nuclear pore complex | −4.5 |
| YOR090C | PTC5 | Mitochondrial type 2C protein phosphatase (PP2C) | −3.6 |
| YGR213C | RTA1 | Protein involved in 7-aminocholesterol resistance | −3.3 |
| YDR434 W | GPI17 | Transmembrane protein | −3.2 |
| YBR111C | YSA1 | Nudix hydrolase family member with ADP-ribose pyrophosphatase activity | −3.2 |
| YOL131 W | Putative protein of unknown function | −3.2 | |
| YER061C | CEM1 | Mitochondrial beta-keto-acyl synthase | −3.1 |
| YNR058 W | BIO3 | 7,8-diamino-pelargonic acid aminotransferase (DAPA) | −3.1 |
| YCL032 W | STE50 | Adaptor protein for various signaling pathways | −3.0 |
| YOR353C | SOG2 | Key component of the RAM signaling network | −3.0 |