Steroids alone |
Prednisolone 0.5 mg/kg for 2–4 weeks then taper by 5 mg/1–2 weeks |
34 % of relapses |
|
Steroids + immunomodulator |
Prednisolone 0.5 mg/kg for 2–4 weeks then taper by 5 mg/week |
76 % of relapses |
1st Line |
Azathioprine 2 mg/kg |
71 % of relapses |
2nd Line |
Mycophenolate 500 mg-1,000 mg b.d. |
5/13 |
(If azathiopine intolerant, 13 patients) |
Methotrexate 15 mg weekly |
4/13 |
|
Mercaptopurine |
2/13 |
|
Low-dose prednisolone 5 mg o.d. |
2/13 |
|
If relapse on immunomodulator |
Prednisolone |
8/8 |
(8 patients) |
+ increase azathioprine dose or |
4/8 |
|
+ change immunomodulator |
4/8 |