Table 3.
Association Between Dietary Pattern and Risk of Classic Hodgkin Lymphoma by Tumor Epstein-Barr Virus Status, Overall and by Age Group for Selected Dietary Patterns, Connecticut and Massachusetts, 1997–2000
| cHL by Age Group and Quartile | High Meat Dietary Pattern |
Desserts/Sweets Dietary Pattern |
||||||
|---|---|---|---|---|---|---|---|---|
| No. of Cases |
No. of Controls |
Odds Ratioa |
95% CI | No. of Cases |
No. of Controls |
Odds Ratioa |
95% CI | |
| EBV-Positive Tumors | ||||||||
| Overall | ||||||||
| Quartile 1 | 17 | 141 | 1.00 | Referent | 19 | 157 | 1.00 | Referent |
| Quartile 2 | 15 | 141 | 0.91 | 0.43, 1.94 | 22 | 144 | 1.31 | 0.67, 2.55 |
| Quartile 3 | 16 | 146 | 0.99 | 0.46, 2.14 | 15 | 130 | 0.96 | 0.47, 1.98 |
| Quartile 4 | 25 | 135 | 1.74 | 0.73, 4.17 | 17 | 132 | 1.06 | 0.52, 2.16 |
| Ptrendb | 0.16 | 0.93 | ||||||
| Age <50 yearsc | ||||||||
| Quartile 1 | 12 | 107 | 1.00 | Referent | 16 | 135 | 1.00 | Referent |
| Quartile 2 | 10 | 105 | 0.92 | 0.37, 2.30 | 15 | 125 | 1.04 | 0.49, 2.23 |
| Quartile 3 | 10 | 122 | 0.84 | 0.33, 2.18 | 13 | 97 | 1.16 | 0.53, 2.55 |
| Quartile 4 | 22 | 117 | 2.33 | 0.83, 6.52 | 10 | 94 | 0.87 | 0.37, 2.04 |
| Ptrendb | 0.07 | 0.79 | ||||||
| Age ≥50 years | ||||||||
| Quartile 1 | 5 | 34 | 1.00 | Referent | 22 | 1.00 | Referent | |
| Quartile 2 | 5 | 36 | 0.68 | 0.16, 2.85 | 7 | 19 | 2.85 | 0.60, 13.60 |
| Quartile 3 | 6 | 24 | 1.33 | 0.32, 5.60 | 2 | 33 | 0.42 | 0.06, 2.80 |
| Quartile 4 | 3 | 18 | 0.68 | 0.10, 4.50 | 7 | 38 | 1.27 | 0.27, 5.94 |
| Ptrendb | 0.91 | 0.71 | ||||||
| EBV-Negative Tumors | ||||||||
| Overall | ||||||||
| Quartile 1 | 59 | 141 | 1.00 | Referent | 52 | 157 | 1.00 | Referent |
| Quartile 2 | 67 | 141 | 1.23 | 0.79, 1.89 | 62 | 144 | 1.24 | 0.80, 1.92 |
| Quartile 3 | 65 | 146 | 1.24 | 0.78, 1.96 | 67 | 130 | 1.53 | 0.99, 2.36 |
| Quartile 4 | 64 | 135 | 1.47 | 0.84, 2.57 | 74 | 132 | 1.77 | 1.15, 2.74 |
| Ptrendb | 0.21 | 0.008 | ||||||
| Age <50 yearsc | ||||||||
| Quartile 1 | 53 | 107 | 1.00 | Referent | 45 | 135 | 1.00 | Referent |
| Quartile 2 | 56 | 105 | 1.14 | 0.70, 1.83 | 54 | 125 | 1.23 | 0.77, 1.97 |
| Quartile 3 | 56 | 122 | 1.03 | 0.62, 1.70 | 59 | 97 | 1.80 | 1.13, 2.88 |
| Quartile 4 | 55 | 117 | 1.15 | 0.62, 2.11 | 62 | 94 | 2.11 | 1.31, 3.41 |
| Ptrendb | 0.77 | 0.001 | ||||||
| Age ≥50 years | ||||||||
| Quartile 1 | 6 | 34 | 1.00 | Referent | 7 | 22 | 1.00 | Referent |
| Quartile 2 | 11 | 36 | 1.81 | 0.57, 5.74 | 8 | 19 | 1.00 | 0.29, 3.48 |
| Quartile 3 | 9 | 24 | 2.67 | 0.73, 9.73 | 8 | 33 | 0.67 | 0.21, 2.18 |
| Quartile 4 | 9 | 18 | 4.64 | 1.03, 20.86 | 12 | 38 | 0.77 | 0.24, 2.46 |
| Ptrendb | 0.04 | 0.60 | ||||||
Abbreviations: CI, confidence interval; EBV, Epstein-Barr virus.
a All logistic regression models adjusted for sex, state of residence, total caloric intake, and body mass index.
b Test for trend from logistic regression model, modeling the median of each quartile as a semicontinuous variable.
c Age defined as the age at diagnosis for cases and the age at study entry for controls.