Table 2.
SNP | CHR | A1 | Genes | MAF | N | BETA | STAT | P | Adjusted Empirical P value | Phenotype |
---|---|---|---|---|---|---|---|---|---|---|
rs6558484 | 8 | C | DLGAP2 | 0.45 | 17 | −1.373 | −4.53 | 0.000565 | 0.3071 | OFC (White Matter) |
rs7014992 | 8 | G | DLGAP2 | 0.45 | 17 | −1.373 | −4.53 | 0.000565 | 0.3071 | OFC (White Matter) |
rs1116345 | 18 | T | DLGAP1 | 0.3 | 19 | 1.726 | 3.951 | 0.001282 | 0.3884 | ACC Volume |
rs342483 | 18 | C | DLGAP1 | 0.3 | 19 | 1.726 | 3.951 | 0.001282 | 0.3884 | ACC Volume |
rs6994849 | 8 | A | DLGAP2 | 0.475 | 17 | −3.605 | −4.061 | 0.001348 | 0.4504 | OFC Volume |
rs10814988 | 9 | A | SLC1A1 | 0.2 | 19 | 2 | 3.86 | 0.001541 | 0.4032 | ACC (Grey Matter) |
rs1558024 | 8 | G | DLGAP2 | 0.475 | 17 | 3.343 | 3.985 | 0.001555 | 0.4856 | OFC Volume |
rs3738081 | 8 | C | GRIK3 | 0.475 | 19 | 0.9366 | 3.789 | 0.001781 | 0.45 | ACC (White Matter) |
rs6558484 | 8 | C | DLGAP2 | 0.45 | 17 | −3.728 | −3.911 | 0.001789 | 0.5223 | OFC Volume |
rs7014992 | 8 | G | DLGAP2 | 0.45 | 17 | −3.728 | −3.911 | 0.001789 | 0.5223 | OFC Volume |
rs8097308 | 18 | C | DLGAP1 | 0.475 | 17 | 0.9312 | 3.899 | 0.001828 | 0.5664 | OFC(White Matter) |
rs2956913 | 8 | G | DLGAP2 | 0.45 | 17 | 3.087 | 3.754 | 0.002411 | 0.6038 | OFC Volume |
rs11612284 | 12 | A | GRIN2B | 0.2 | 20 | 2.138 | 3.565 | 0.002584 | 0.6546 | Thalamus Volume |
rs10094463 | 8 | A | DLGAP2 | 0.475 | 17 | 4.265 | 3.685 | 0.002749 | 0.6425 | OFC Volume |
rs301430 | 9 | C | SLC1A1 | 0.45 | 20 | −1.469 | −3.456 | 0.003251 | 0.6401 | Thalamus Volume |
rs11842338 | 13 | A | SLITRK5 | 0.175 | 20 | −2.229 | −3.436 | 0.003394 | 0.6546 | Thalamus Volume |
rs12215960 | 6 | G | GRIK2 | 0.15 | 19 | 0.7756 | 3.451 | 0.003567 | 0.6794 | ACC(White Matter) |
rs10459061 | 12 | A | GRIN2B | 0.1 | 19 | −2.444 | −3.39 | 0.004038 | 0.7135 | ACC(Grey Matter) |
rs17833967 | 12 | C | GRIN2B | 0.1 | 19 | −2.444 | −3.39 | 0.004038 | 0.7135 | ACC(Grey Matter) |
rs7541937 | 1 | T | DLGAP3 | 0.45 | 17 | 0.8712 | 3.463 | 0.004203 | 0.7758 | OFC(White Matter) |
rs2301963 | 8 | C | DLGAP2 | 0.475 | 17 | −1.355 | −3.443 | 0.004366 | 0.7844 | OFC(White Matter) |
rs10485270 | 6 | A | GRIK2 | 0.175 | 19 | 0.7689 | 3.328 | 0.00459 | 0.76 | ACC(White Matter) |
rs9390764 | 6 | A | GRIK2 | 0.175 | 19 | 0.7689 | 3.328 | 0.00459 | 0.76 | ACC(White Matter) |
rs1116345 | 18 | T | DLGAP1 | 0.3 | 19 | 1.255 | 3.327 | 0.004596 | 0.7934 | ACC(Grey Matter) |
rs342483 | 18 | C | DLGAP1 | 0.3 | 19 | 1.255 | 3.327 | 0.004596 | 0.7543 | ACC(Grey Matter) |
rs1558024 | 8 | G | DLGAP2 | 0.475 | 17 | 1.071 | 3.406 | 0.004692 | 0.7844 | OFC(White Matter) |
rs2956929 | 8 | A | DLGAP2 | 0.5 | 17 | 2.833 | 3.401 | 0.004733 | 0.7898 | OFC Volume |
rs2300266 | 12 | G | GRIN2B | 0.175 | 20 | 1.797 | 3.275 | 0.004766 | 0.7638 | Thalamus Volume |
A1: Minor allele
MAF: minor allele frequency
N: number of subjects with non-missing data for the brain region volume.
Beta: Regression coefficient (non-standardized)
STAT: Coefficient t-statistic
Adjusted Empirical P value: based on max (T) permutation (n = 50,000)
ACC: Anterior Cingulate Cortex
OFC: Orbital Frontal Cortex