Table 5.

Gene Ontology enrichment (Biological Process) of predicted marker genes for the examined tissues

GO ID	GO	p-value	Expected count	Gene count	Size
Midbrain
GO:0007409	axonogenesis	4.49×10−22	46.71	118	489
GO:0010975	regulation of neuron projection development	5.58×10−20	21.4	70	224
GO:0006836	neurotransmitter transport	3.93×10−18	12.42	49	130
GO:0051969	regulation of transmission of nerve impulse	9.65×10−16	19.11	59	200
GO:0016358	dendrite development	6.24×10−13	12.51	42	131
Heart atrium
GO:0006941	striated muscle contraction	3.12×10−27	3.82	37	97
GO:0060047	heart contraction	3.34×10−27	5.76	44	146
GO:0048738	cardiac muscle tissue development	9.63×10−25	5.56	41	141
GO:0090257	regulation of muscle system process	4.29×10−24	5.76	41	146
GO:0030239	myofibril assembly	1.6×10−26	1.66	26	42
Kidney cortex
GO:0055085	transmembrane transport	2.03×10−18	29.19	83	757
GO:0007588	excretion	1.83×10−10	2.47	17	64
GO:0072006	nephron development	6.35×10−09	3.43	18	89
GO:0006814	sodium ion transport	8.87×10−08	4.47	19	116
GO:0072348	sulfur compound transport	1.74×10−05	0.89	7	23
Liver
GO:0008202	steroid metabolic process	8.68×10−46	15.33	90	267
GO:0032787	monocarboxylic acid metabolic process	3.34×10−35	24.57	100	428
GO:0006805	xenobiotic metabolic process	4.1×10−30	8.04	53	140
GO:0044282	small molecule catabolic process	2×10−28	14.7	69	256
GO:1901605	alpha-amino acid metabolic process	7.38×10−25	11.54	57	201
Lung
GO:0002684	positive regulation of immune system process	2.53×10−37	40.21	134	606
GO:0006954	inflammatory response	2.23×10−25	32.64	101	492
GO:0001816	cytokine production	4.95×10−25	31.32	98	472
GO:0046649	lymphocyte activation	1.2×10−24	31.12	97	469
GO:0009607	response to biotic stimulus	2.18×10−24	39.28	111	592

Column labels are as follows: GO ID is the GO identifier; GO is the description of the GO term; p-value is the hypergeometric p-value for over-representation of each GO term; Expected/Gene Count are the expected and actual gene counts; and Size is the number of genes within each GO term