Fig 3. Phylogenetic analysis of the NA gene of influenza B viruses in Malaysia from 2012 to 2014.

NA sequences of Malaysian influenza B viruses were compared with WHO recommended candidate vaccine and reference strains. The phylogeny was reconstructed using maximum likelihood (ML) method. Bootstrap values (>60%) and amino acid substitutions are mapped to key branches. Intra-and inter-clade reassortants are indicated as boxes. Yamagata Clade 3 (Yam-3) (blue), Yamagata Clade 2 (Yam-2) (orange) and Victoria Clade 1 (Vic-1) (green) are indicated. Scale bar represents a genetic distance of 0.008 substitutions/site. Phylogenetic tree for NA gene with complete taxa identity is shown in S2 Fig.