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. 2015 Aug 27;10(8):e0136254. doi: 10.1371/journal.pone.0136254

Table 5. Comparison on the demographic and clinical characteristics of patients infected by influenza B Victoria and Yamagata lineages.

Victoria Lineage Yamagata Lineage Yamagata vs Victoria (ref.)
Characteristics (n = 56) (n = 114) p OR (95% CI) B SE p aOR 95% CI
Demographic Features
Mean (± S.D.) age in years 32.11 ± 16.18 43.58 ± 18.22 <0.001 a - - - - - -
No. (%) of patients≤ 24 yrs old 21 (37.5) 20 (17.5) 0.006 b - ref. 0.085 c ref.
No. (%) of patients25-55 yrs old 27 (48.2) 35 (30.7) - 0.576 0.459 0.210 c 1.779 0.723–4.377
No. (%) of patients≥ 56 years old 8 (14.3) 59 (51.8) - 1.466 0.662 0.027 c 4.33 1.184–15.838
Clinical Features
Median (IQR) days onset of symptoms 4 (2–6) 4 (3–5) 0.670 a - -0.032 0.089 0.722 c 0.969 0.814–1.153
No. (%) of patients with:
Sneezing Yes 44 (78.6) 81 (71.1) 0.296 b 1.49 (0.70–3.18) -0.497 0.522 0.341 c 0.608 0.219–1.692
No 12 (21.4) 33 (28.9) ref. ref.
Nasal Discharge Yes 43 (76.8) 88 (77.2) 0.953 b 0.98 (0.46–2.09) 0.565 0.523 0.280 c 1.76 0.631–4.910
No 13 (23.2) 26 (22.8) ref. ref.
Nasal Congestion Yes 44 (78.6) 71 (62.3) 0.033 b 2.22 (1.06–4.67) -1.042 0.513 0.042 c 0.353 0.139–0.963
No 12 (21.4) 43 (37.7) ref. ref.
Headache Yes 40 (71.4) 89 (78.1) 0.341 b 0.70 (0.34–1.46) 1.282 0.514 0.013 c 3.603 1.316–9.896
No 16 (28.6) 25 (21.9) ref. ref.
Sore throat Yes 46 (82.1) 74 (64.9) 0.02 b 2.49 (1.14–5.45) -1.42 0.542 0.009 c 0.242 0.084–0.699
No 10 (17.9) 40 (35.1) ref. ref.
Hoarseness of voice Yes 43 (76.8) 93 (81.6) 0.463 b 0.75 (0.34–1.63) 0.874 0.523 0.095 c 2.398 0.860–6.683
No 13 (23.2) 21 (18.4) ref. ref.
Muscle ache Yes 45 (80.4) 97 (85.1) 0.434 b 0.72 (0.31–1.66) -0.467 0.583 0.423 c 0.627 0.200–1.964
No 11 (19.6) 17 (14.9) ref. ref.
Cough Yes 54 (96.4) 109 (95.6) 0.802 b 1.24 (0.23–6.60) -0.681 1.059 0.520 c 0.506 0.064–4.032
No 2 (3.6) 5 (4.4) ref. ref.

n: number of patients; OR: odds ratio; CI: confidence interval; B: coefficient; SE: standard error; SD: standard deviation; aOR: adjusted odds ratio; ref: reference group; p: level of significance (2-tailed) at the 0.05 level

ap-value calculated by Independent Samples t-Test

bp-value calculated by Pearson’s Chi-square test/Fischer’s Exact test

cp-value calculated by Binary Logistic Regression