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. 2015 Aug 28;14:333. doi: 10.1186/s12936-015-0833-x

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© Shelton et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Plot for 178 SNPs with logged anti-malarial antibody levels. Values of –log₁₀ p-values plotted against chromosomal positions; only the lowest meta-analysis p-value for each SNP-antibody association is plotted. The red dotted line indicates a Bonferroni threshold p-value of 6 × 10⁻⁵. Each colour represents a different anti-malarial antibody while the shape of the point represents the genetic model of best fit for the SNP-antibody association: (circle) for additive, (triangle) for dominant, and (square) for heterozygote and (plus) for recessive. Adjusted for age, gender, microscopy result, village (>20), ethnicity (>20), sample month (>20) and study.