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. 2015 Jun 26;146(1):59–69. doi: 10.1111/imm.12480

Figure 1.

Figure 1

Small intestine intraepithelial lymphocytes (SI-IELs) in polymeric immunoglobulin receptor-positive (pIgR+/+ or pIgR+/−) mice and pIgR−/− mice. (a) SI-IELs were prepared from pIgR+/+ mice (11–12 weeks old, n = 5, ■) and pIgR−/− mice (11–12 weeks old, n = 7, □). By multiplying the total number of SI-IELs by the proportion of T-cell receptor-αβ-positive (TCR-αβ+) cells or TCR-γδ+ cells, the numbers of αβ-IELs or γδ-IELs were calculated. (b) Change of αβ-IELs and γδ-IELs in the newborn pIgR+/− and pIgR−/− mice. Male pIgR+/− mice and female pIgR−/− mice were crossbred and the newborn pIgR+/− mice (●) or pIgR−/− mice (○) were nursed by pIgR−/− mice. Numbers of αβ-IELs and γδ-IELs were examined 3, 5 and 7 weeks after the birth. Data are shown as mean ± SD of two to three mice. *P < 0·05, **P < 0·01.