Figure 6.

Intestinal permeability of small intestine (SI) of polymeric immunoglobulin receptor-positive (pIgR^+/+) mice and pIgR^−/− mice. Loops were generated at duodenum and ileum of mice under isoflurane-anaesthesia, and FITC-dextran or rhodamine B isothiocyanate-dextran solutions was injected into the loops, respectively. By measuring the fluorescence intensity in the serum collected at intervals, permeability of SI was evaluated. Closed circles show the data of each mouse and the bars represent the mean value.