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Transendothelial electrical resistance (TEER) measurements in the in vitro blood–brain barrier in response to treatment withC5a/lupus serum and C5a antagonist
| Treatments | TEER pre-treatment | TEER post-treatment | P value |
|---|---|---|---|
| Blank | 140 ± 2·0 | 123·33 ± 10·26 | NS |
| Untreated control | 282·60 ± 3·06 | 285·33 ± 3·06 | NS |
| C5a 0·1 μg/ml | 292·66 ± 7·57 | 186·66 ± 8·33 | P < 0·006 |
| Lupus serum | 288·67 ± 4·62 | 128·66 ± 4·16 | P < 0·0001 |
| C5a antagonist + lupus serum | 288 ± 4·0 | 254 ± 4·0 | P < 0·015 |
