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. 2015 Jul 14;146(1):157–162. doi: 10.1111/imm.12491

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© 2015 John Wiley & Sons Ltd

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Relative reactivity of follicular helper T (Tfh) and non-Tfh cells for haemagglutinin (HA) and nucleoprotein (NP) in individual healthy human donors. The distribution of HA-specific and NP-specific, interferon-γ (IFN-γ) secreting cells as determined by IFN-γ cytokine assay (left) or the surface expression of CD137 and CD69 after 30 hr of simulation with peptide pools (right) from each donor was calculated as a ratio of total NP-specific/HA-specific cells (NP/HA). Data were analysed using the Wilcoxon signed-rank test.