Table 2.

Changes in body weight, blood pressure, and plasma cholesterol from baseline to the end of period 1 (24 weeks) and period 2 (48 weeks). The decrease in blood pressure and plasma cholesterol trend to be lower following ACTIVE treatment in period 2 as compared to CONTROL treatment. There was a large variability in weight loss among patients

	Treatment	Baseline	24 weeks	48 weeks	Difference from baseline at 48 weeks
Weight (kg)	Control to Active	105.8±3.5	−2.32±0.94	−2.82±0.88
	Active to Control	105.5±4.7	−3.35±2.56	−3.39±3.14
Systolic BP (mmHg)	Control to Active	136.8±2.7	131.8±2.5	133.2±1.9	−3.6
	Active to Control	133.3±2.7	132.7±4.1	135.8±3.1	+2.5
Diastolic BP (mmHg)	Control to Active	87.1±1.7	83.9±1.6	83.7±1.4	−3.4
	Active to Control	82.2±2.3	82.1±2.6	84.9±2.5	+2.7
Plasma cholesterol (mmol/L)	Control to Active	5.04±0.27	4.70±0.26	4.78±0.21	−0.26
	Active to Control	4.62±0.28	4.94±0.25	4.65±0.29	−0.03