Table 1.
Rabbit | Length of Implantation (Months) |
Corneal Clarity | Epithelial and Stromal Defects | Neovascularization | Polymer Extrusion |
---|---|---|---|---|---|
1 | 2 | Clear | None | No | No |
2 | 2 | Clear | None | No | No |
3 | 2 | Clear | None | No | No |
4 | 2 | Diffuse haze across the implant region | Areas of corneal thinning over the implant (2 mo.) | No | No |
5 | 2 | Diffuse haze across the implant region | None | No | No |
6 | 2 | Diffuse haze across the implant region | None | No | No |
7 | 6 | Clear | None | No | No |
8 | 6 | Opacity across the entire cornea | 1 epithelial defect over the polymer edge (3 mo.) | Yes | No |
9 | 9 | Moderate haze across the implant region | Areas of corneal thinning over the implant, extrusion (4 mo.) | No | 4 mo |
10 | 9 | Clear | 1 epithelial defect over the polymer edge, 1 area of corneal thinning (8 mo.) | No | No |
11 | 12 | Clear | 1 epithelial defect over the polymer edge (at 11mo.) | No | No |
12 | 16 | Clear | 1 area of corneal thinning over the polymer; several areas of thinning at the polymer edge (14 mo.) | No | No |
13-control | 2 | Clear | None | No | No |