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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: J Biomed Mater Res A. 2015 Mar 27;103(10):3157–3165. doi: 10.1002/jbm.a.35453

Table 1.

Clinical Examination

Rabbit Length of
Implantation
(Months)
Corneal Clarity Epithelial and Stromal Defects Neovascularization Polymer
Extrusion
1 2 Clear None No No
2 2 Clear None No No
3 2 Clear None No No
4 2 Diffuse haze across the implant region Areas of corneal thinning over the implant (2 mo.) No No
5 2 Diffuse haze across the implant region None No No
6 2 Diffuse haze across the implant region None No No
7 6 Clear None No No
8 6 Opacity across the entire cornea 1 epithelial defect over the polymer edge (3 mo.) Yes No
9 9 Moderate haze across the implant region Areas of corneal thinning over the implant, extrusion (4 mo.) No 4 mo
10 9 Clear 1 epithelial defect over the polymer edge, 1 area of corneal thinning (8 mo.) No No
11 12 Clear 1 epithelial defect over the polymer edge (at 11mo.) No No
12 16 Clear 1 area of corneal thinning over the polymer; several areas of thinning at the polymer edge (14 mo.) No No
13-control 2 Clear None No No