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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Lab Invest. 2015 Jun 22;95(9):995–1004. doi: 10.1038/labinvest.2015.71

Figure 2.

Figure 2

Overexpression of wild-type FBXW7 downregulates the protein level of ENO1. Wild-type FBXW7 was re-introduced into HCT116 FBXW7−/− and HEK293T cells. At the same time, FBXW7 ΔF (F-box deletion) was also introduced into HEK293T cells. Western blotting assay on the whole cell lysates of HCT116 FBXW7−/− (a) and HEK293T cells (b) using the anti-ENO1 and anti-FBXW7 antibodies. The graph shows quantitative analysis. All results are representative of three independent experiments. **P < 0.01 based on Student’s t-test. EV: empty vector.