Table 1. Characteristics of the 1,176 patients.

Features at diagnosis			Risk group
			SR	HR	ER	T	F	Total
			n = 386	n = 509	n = 128	n = 78	n = 75	n = 1,176
Age (year)		Average ± SD (median)	4.1 ± 2.1 (4)	6.3 ± 4.3 (5)	7.0 ± 4.2 (6)	8.0 ± 3.5 (8)	7.7 ± 4.4 (7)	5.8 ± 3.9 (5)
at onset		< 10	386	370	89	53	47	945
		≥ 10	0	139	39	25	28	231
Sex		Female	195	232	60	11	28	526
		Male	191	277	68	67	47	650
Immuno-phenotype		B-cell	386	509	98	0	39	1,032
		Mixed	0	0	25	0	13	38
		T-cell	0	0	0	78	21	99
		Undifferentiated	0	0	5	0	2	7
Leukocyte count		Range (median)	0.37–9.98 (3.70)	0.43–401 (13.2)	1.00–420 (19.1)	0.72–819 (54.4)	1.10–816 (31.3)	0.72–819 (7.50)
at onset (× 109/L)		< 20	386	317	69	26	31	829
		≥ 20-< 50	0	115	31	11	18	175
		≥ 50	0	77	28	41	26	172
Chromosome/		Normal karyotype	189	203	56	44	28	520
Genetic abnormality		Hyperdiploid	99	97	17	1	2	216
		ETV6-RUNX1	87	88	17	0	3	195
		TCF3-PBX1	0	68	8	0	2	78
Extramedullary disease		Present	0	18	5	9	5	37
Obesity	BMI	< 22%	361	461	114	68	63	1,067
		≥ 22%	3	19	8	2	5	37
	BMIp	< 85%	324	398	100	58	59	939
		≥ 85%	40	82	22	12	9	165
	Obesity index	< 20%	353	444	111	64	63	1,035
		≥ 20%	11	36	11	6	5	69
	No data		22	29	6	8	7	72
Down syndrome		Present	6	10	5	0	2	23

ER, extremely high risk; F, induction failure; HR, high risk; L, liter; SD, standard deviation; SR, standard risk

T, T-cell type; n, number; SD, standard deviation.