Table 3. Univariate analysis of L-asp-related hyperglycemia.
During entire treatment | Induction phase | Maintenance phase | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Odds ratio | 95% CI | p-value | Odds ratio | 95% CI | p-value | Odds ratio | 95% CI | p-value | ||
Age at onset (yrs) | ||||||||||
1–4 vs 5–18 | 1.000 | 1.000 | 1.000 | |||||||
4.534 | 2.441–8.422 | <0.0001 | 1.330 | 1.330–3.500 | 0.564 | 11.157 | 3.323–37.462 | <0.0001 | ||
1–9 vs 10–18 | 1.000 | 1.000 | 1.000 | |||||||
5.442 | 3.308–8.953 | <0.0001 | 3.731 | 1.424–9.778 | 0.0074 | 7.299 | 3.882–15.247 | <0.0001 | ||
1–14 vs 15–18 | 1.000 | 1.000 | 1.000 | |||||||
3.656 | 1.455–9.183 | 0.006 | 7.629 | 2.082–27.954 | 0.002 | 1.685 | 0.493–5.759 | 0.405 | ||
Sex | ||||||||||
female | 1.000 | 1.000 | 1.000 | |||||||
male | 0.824 | 0.506–1.340 | 0.4342 | 1.158 | 0.432–3.453 | 0.7065 | 0.519 | 0.281–0.957 | 0.0358 | |
Risk | ||||||||||
SR | 1.000 | 1.000 | - | - | - | |||||
HR | 3.670 | 1.761–7.646 | 0.0005 | 0.628 | 0.217–2.630 | 0.6601 | 1.000 | |||
ER | 4.735 | 1.974–11.361 | 0.0005 | 2.043 | 0.434–7.825 | 0.4069 | 1.001 | 0.449–2.234 | 0.9981 | |
F | 1.148 | 0.243–5.421 | 0.8620 | - | - | - | - | - | - | |
T | 2.264 | 0.679–7.547 | 0.1833 | 1.667 | 0.330–8.415 | 0.5363 | 0.286 | 0.067–1.216 | 0.0902 | |
BMI | ||||||||||
< 22% | 1.000 | 1.000 | 1.000 | |||||||
≥ 22% | 4.713 | 2.064–10.761 | 0.0002 | 6.636 | 1.822–24.177 | 0.0041 | 6.716 | 2.385–18.913 | 0.0003 | |
BMI percentile | ||||||||||
< 85% | 1.000 | 1.000 | 1.000 | |||||||
≥ 85% | 2.042 | 1.147–3.637 | 0.0153 | 2.414 | 0.839–6.945 | 0.1021 | 1.931 | 0.953–3.911 | 0.0677 | |
Obesity index | ||||||||||
< 20% | 1.000 | 1.000 | 1.000 | |||||||
≥20% | 2.908 | 1.413–5.984 | 0.0037 | 3.315 | 0.930–11.823 | 0.0647 | 2.805 | 1.160–6.783 | 0.0221 | |
Down syndrome | ||||||||||
Absent | 1.000 | 1.000 | 1.000 | |||||||
Present | 3.286 | 1.086–9.946 | 0.0352 | 2.975 | 0.378–23.430 | 0.3005 | 3.853 | 0.755–19.671 | 0.1049 |
BMI, body mass index; CI, Confidence interval; ER, extremely high risk; F, induction failure; HR, high risk; SD, standard deviation; SR, standard risk; T, T-cell type.