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. 2015 Aug 28;10(8):e0136746. doi: 10.1371/journal.pone.0136746

Fig 2. Ribavirin inhibited the signaling pathway of mTOR/eIF4E in SUP-B15.

Fig 2

A. The SUP-B15 cells were treated with different concentrations of ribavirin for 48h, and the proteins in mTOR/eIF4E signaling pathway and Mcl-1 were detected by western bolt analysis. B. The SUP-B15 cells were incubated in 60μM ribavirin for 24, 48, 72h, and the mTOR/eIF4E pathway expression was detected by western bolt analysis. C. The expression of mTOR/eIF4E pathway and Mcl-1 in SUP-B15 cells after treated with ribavirin (30μM), imatinib (10μM) alone, and 30μM ribavirin plus 10μM imatinib for 48h.