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. 2015 Aug 28;10(8):e0136615. doi: 10.1371/journal.pone.0136615

Fig 6. Levels of spontaneous apoptosis of ALL blasts depend on patient age and μ–calpain amount.

Fig 6

Apoptosis was determined as the proportion of AnnexinV+ blasts and plotted against the amount of μ–calpain in the blasts (A, N = 17, r = -0.54, p< 0.05) and against patients’ age (B, N = 39, r = -0.31, p< 0.05). See Materials and Methods for details. When the patients were subdivided into below and above 10 years of age subgroups, the latter were characterized by significantly lower apoptosis (C, asterisk signifies p = 0.01) and significantly higher proportion of the μ–calpain positive blasts (D, asterisk signifies p = 0.04). N (1–10 years old ALL patients) = 29, N(>10 years old ALL patients) = 10.