Table 2. Partial correlations analysis of variables associated with circulating HMGB1 concentration in study population.

	Plasma HMGB1		Plasma HMGB1 (age- and sex-adjusted)		Plasma HMGB1 (age-, sex- and BMI adjusted)
variables	r	p	r	p	r	p
Age(year)	0.335	<0.001	-	-	-	-
BMI	0.777	<0.001	0.419	<0.001	-	-
WHR	0.450	<0.001	0.317	<0.001	0.310	<0.001
SBP	0.278	<0.001	0.289	<0.001	0.166	0.041
DBP	0.263	0.001	0.207	0.010	0.214	0.008
FPG	0.280	<0.001	0.212	0.008	0.104	0.037
2hPG	0.229	0.004	0.159	0.050	0.035	0.067
HbA1C	0.244	0.002	0.379	<0.001	0.132	0.104
FINS	0.360	<0.001	0.417	<0.001	0.127	0.018
HOMA-IR	0.447	<0.001	-0.393	<0.001	0.264	0.024
HOMA-β	-0.399	<0.001	0.184	0.023	-0.132	0.039
Cre	0.156	0.053	-0.244	0.002	0.055	0.504
HDL-c	-0.232	0.004	0.039	0.631	-0.160	0.049
LDL-c	0.052	0.519	0.028	0.734	0.111	0.175
TC	0.013	0.875	0.257	0.001	0.104	0.204
TG	0.170	0.030	0.443	<0.001	0.220	0.006
IL-6	0.494	<0.001	0.792	<0.001	0.193	0.017

BMI, body mass index; Wc, waist circumference; WHR, waist hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; 2hPG, 2h postchallenge plasma glucose; HbA_1C, glycated hemoglobin; FINS, fasting serum insulin; HOMA-IR, Homeostasis Model Assessment for insulin resistance; HOMA-β, Homeostasis Model Assessment for beta-cell function; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein-cholesterol; LDL-c, low-density lipoprotein-cholesterol; IL-6, interleukin- 6.