Table 2.
The concentrations at which 50 and 90 % of infections are prevented under the various conditions of copper phthalocyanine sulfate (CuPcS) exposure: HIV pre-treated with CuPcS; peripheral blood mononuclear cells (PBMC) pre-treated with CuPcS; simultaneous addition of HIV, PBMCs, and CuPcS; and pre-incubation of HIV and PBMCs with subsequent addition of CuPcS
CuPcS Inhibition of HIV-1BAL Infection of PBMCs | ||
---|---|---|
EC50 μg/ml | EC90 μg/ml | |
HIV pre-treated | 53.31 | 184.7 |
PBMCs pre-treated | 42.96 | 147.2 |
CuPcS added post-infection | 26.11 | 215.3 |
Combined addition | 54.72 | 186.7 |
Pre (100 μg/mL)- and post-treatment | Undefined | Undefined |