Table 2. Prevalence (%) of Baseline Characteristics in Individuals with New Onset Atrial Fibrillation.
| No. atrial fibrillation | Decade | P for Trend† | Trend Direction | ||||
|---|---|---|---|---|---|---|---|
| 1958-1967 | 1968-1977 | 1978-1987 | 1988-1997 | 1998-2007 | |||
| 70 | 178 | 284 | 399 | 434 | |||
| Current smoking | 27(40•9) | 35(22•3) | 60(21•7) | 62(15•6) | 55(12•7) | 0•0002 | ↓ |
| Alcohol consumption | |||||||
| None | 25(42•4) | 53(31•7) | 127(46•7) | 168(42•7) | 186(44•0) | 0•64 | - |
| Mild | 28(47•5) | 92(55•1) | 122(44•9) | 200(50•9) | 214(50•6) | 0•28 | - |
| Moderate or heavy | 6(10•2) | 22(13•2) | 23(8•5) | 25(6•4) | 23(5•4) | 0•005 | ↓ |
| Body mass index, kg/m2 | |||||||
| Normal, <25 | 20(30•3) | 56(35•7) | 107(39•9) | 115(30•4) | 105(27•7) | 0•0009 | ↓ |
| Overweight, 25 to <30 | 28(42•4) | 68(43•3) | 101(37•7) | 173(45•8) | 140(36•9) | 0•42 | - |
| Obese, ≥30 | 18(27•3) | 33(21•0) | 60(22•4) | 90(23•8) | 134(35•4) | <0•0001 | ↑ |
| Systolic blood pressure, mm Hg | |||||||
| Optimal, <120 | 20(30•3) | 56(35•7) | 107(39•9) | 115(30•4) | 105(27•7) | <0•0001 | ↑ |
| Normal, 120-129 | 28(42•4) | 68(43•3) | 101(37•7) | 173(45•8) | 140(36•9) | 0•001 | ↑ |
| High-normal 130-139 | 18(27•3) | 33(21•0) | 60(22•4) | 90(23•8) | 134(35•4) | 0•009 | ↑ |
| Stage I hypertension, 140-159 | 20(30•3) | 56(35•7) | 107(39•9) | 115(30•4) | 105(27•7) | 0•001 | ↓ |
| Stage II-IV hypertension ≥160 | 28(42•4) | 68(43•3) | 101(37•7) | 173(45•8) | 140(36•9) | <0•0001 | ↓ |
| Hypertension treatment | 15(22•1) | 55(32•9) | 135(47•7) | 219(55•4) | 257(59•8) | <0•0001 | ↑ |
| Diabetes | 4(5•7) | 25(14•0) | 44(15•7) | 66(16•7) | 80(19•6) | 0•004 | ↑ |
| Electrocardiographic left ventricular hypertrophy | 9(12•9) | 21(11•8) | 19(6•9) | 23(6•2) | 12(2•9) | <0•0001 | ↓ |
| Significant heart murmur | 14(20•0) | 32(18•9) | 52(19•2) | 42(10•7) | 31(8•1) | <0•0001 | ↓ |
| Prevalent heart failure | 4(5•7) | 15(8•4) | 17(6•0) | 23(5•8) | 15(3•5) | 0•009 | ↓ |
| Prevalent myocardial infarction | 6(8•6) | 16(9•0) | 27(9•5) | 45(11•3) | 47(10•8) | 0•27 | - |
All entries are in percentages.
In total 1365 (88•4%) atrial fibrillation cases were identified with index exams. The remaining 179 were excluded from this analysis for missing eligible index exams.
This table presents the age- and sex-adjusted prevalence of baseline characteristics for atrial fibrillation cases with index examination. For each characteristic, prevalence in different decades are predicted values from a logistic model where the characteristic is the outcome variable, decade as main predictor if the trend test is significant, with age and sex as covariates. The observed prevalence by sex is presented in Supplementary Table 2.
P-values are obtained from logistic models adjusting for age and sex fitted on observed data.
The prevalence may not add up to exactly 1 for multiple categorical variables because of rounding.