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Triad alteration in skeletal muscle of triadin KO mouse In addition to the abnormal triad orientation observed in 30% of the triads, some alterations in the structure of all the triads can be visualized using electron microscopy on extensor digitorum longus muscle of triadin KO mice (Oddoux et al. 2009): a flattening of sarcoplasmic reticulum terminal cisternae resulting from the reduction in the amount of CSQ, and an increase in the distance between T-tubules and terminal cisternae.
