Figure 6.

Dependence of the apparent rate constant of ADP release (k_−ADP,app) and the apparent detachment rate (g) on the velocity (A), the sarcomere force (B) and the average strain in the myosin motors (C)

k_−ADP,app is calculated either considering only the concentrations of the attached AM.ADP states (dotted line) or also the concentration of the early detached states (dashed line). g (continuous line) is calculated by dividing the total flux by the sum of the concentrations of all attached states.