TABLE 5.

Unadjusted difference in mean change in outcome parameters in bone marrow cell-treated patients compared with controls based on timing of cell injection after acute MI.

Time of injection	BMC Therapy (n)	Control (n)	Difference in mean (95% CI)	P value
LVEF
0 – 2 days	98	81	1.85 (−0.67, 4.37)	0.15
3 – 10 days	814	625	2.09 (0.54, 3.64)	0.008
> 10 days	142	116	2.74 (−1.88, 7.37)	0.25
Infarct size
0 – 2 days	40	40	−4.41 (−8.22, −0.60)	0.02
3 – 10 days	494	400	−1.00 (−2.52, 0.53)	0.20
> 10 days	100	72	−7.13 (−16.06, 1.81)	0.12
LVESV
0 – 2 days	39	41	−11.14 (−31.17, 8.88)	0.28
3 – 10 days	587	466	−5.76 (−8.37, −3.14)	0.0001
> 10 days	87	60	1.37 (−3.39, 6.12)	0.57
LVEDV
0 – 2 days	39	41	−12.59 (−42.68, 17.50)	0.41
3 – 10 days	587	466	−2.95 (−5.65, −0.25)	0.03
> 10 days	92	65	0.81 (−5.53, 7.16)	0.45

Abbreviations: LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; CI, confidence interval; n, number of patients in each group