Table 7.
Subgroup analysis to examine any potential impact of procedures in control patients on outcome variables.
| Outcome | Difference in mean (95% CI) | BMC Therapy (n) | Control (n) | P value |
|---|---|---|---|---|
|
| ||||
| Cardiac catheterization in control group | ||||
| 2.86 (1.40, 4.32) | ||||
| LVEF | −3.41 (−5.38, −1.44) | 694 | 513 | 0.0001 |
| Infarct scar size | −3.17 (−4.47, – 1.86) | 314 | 222 | 0.0007 |
| LVESV | −2.76 (−4.97, – 0.55) | 374 | 277 | <0.00001 |
| LVEDV | 405 | 312 | 0.01 | |
|
| ||||
| No cardiac catheterization in control group | ||||
| LVEF | 2.97 (1.54, 4.40) | 732 | 567 | <0.0001 |
| Infarct scar size | −1.16 (−3.07, 0.74) | 398 | 337 | 0.23 |
| LVESV | −7.93 (−12.35, −3.51) | 561 | 434 | 0.0004 |
| LVEDV | −1.43 (−6.57, 3.71) | 504 | 379 | 0.59 |
|
| ||||
| BM aspiration in control group | ||||
| LVEF | 1.58 (0.00, 3.17) | 443 | 299 | 0.05 |
| Infarct scar size | 0.05 (−2.72, 2.81) | 178 | 97 | 0.97 |
| LVESV | −3.51 (−6.40, −0.62) | 261 | 194 | 0.02 |
| LVEDV | −4.68 (−12.64, 3.27) | 251 | 184 | 0.25 |
|
| ||||
| No BM aspiration in control group | ||||
| LVEF | 3.40 (2.21, 4.60) | 981 | 779 | <0.00001 |
| Infarct scar size | −2.59 (−4.01, −1.18) | 534 | 462 | 0.0003 |
| LVESV | −7.67 (−10.96, −4.39) | 674 | 517 | <0.00001 |
| LVEDV | −1.73 (−4.13, 0.68) | 658 | 507 | 0.16 |
Abbreviations: LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; BM, Bone marrow; CI, confidence interval; n, number of patients in each group