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. Author manuscript; available in PMC: 2016 Aug 28.
Published in final edited form as: Circ Res. 2015 Jul 9;117(6):558–575. doi: 10.1161/CIRCRESAHA.114.304792

Table 7.

Subgroup analysis to examine any potential impact of procedures in control patients on outcome variables.

Outcome Difference in mean (95% CI) BMC Therapy (n) Control (n) P value

Cardiac catheterization in control group
2.86 (1.40, 4.32)
LVEF −3.41 (−5.38, −1.44) 694 513 0.0001
Infarct scar size −3.17 (−4.47, – 1.86) 314 222 0.0007
LVESV −2.76 (−4.97, – 0.55) 374 277 <0.00001
LVEDV 405 312 0.01

No cardiac catheterization in control group
LVEF 2.97 (1.54, 4.40) 732 567 <0.0001
Infarct scar size −1.16 (−3.07, 0.74) 398 337 0.23
LVESV −7.93 (−12.35, −3.51) 561 434 0.0004
LVEDV −1.43 (−6.57, 3.71) 504 379 0.59

BM aspiration in control group
LVEF 1.58 (0.00, 3.17) 443 299 0.05
Infarct scar size 0.05 (−2.72, 2.81) 178 97 0.97
LVESV −3.51 (−6.40, −0.62) 261 194 0.02
LVEDV −4.68 (−12.64, 3.27) 251 184 0.25

No BM aspiration in control group
LVEF 3.40 (2.21, 4.60) 981 779 <0.00001
Infarct scar size −2.59 (−4.01, −1.18) 534 462 0.0003
LVESV −7.67 (−10.96, −4.39) 674 517 <0.00001
LVEDV −1.73 (−4.13, 0.68) 658 507 0.16

Abbreviations: LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; BM, Bone marrow; CI, confidence interval; n, number of patients in each group