Developmental profiles of the 8 microRNAs in the MPN of female and male rats are shown. Main effects of age, sex, and treatment are indicated above the panels. Post-hoc analyses of significant age effects are indicated as: a, P15 vs P30; b, P15 vs P45; c, P15 vs P90; d, P30 vs P45; e, P30 vs P90 (all p < 0.05). Post-hoc analyses for significant age x treatment interactions are indicated as *p < 0.05, A1221 vs. DMSO at the same age; +p < 0.05, EB vs. DMSO at the same age. Abbreviation: Trt, Treatment.