Developmental profiles of mRNAs in the VMN that were significantly affected by age, treatment, or had age x treatment interactions, in female (A – D) and male (E, F) rats. Main effects are indicated below the panels. Post-hoc analyses for age are indicated as: a, P15 vs P30; b, P15 vs P45; c, P15 vs P90; d, P30 vs P45; e, P30 vs P90; f, P45 vs P90 (all p < 0.05). Age x treatment interaction were found for Lepr and Clock at P45 in females, and for Ar and Clock at P90 in males (*p < 0.05, A1221 vs. DMSO at the same age; +p < 0.05, EB vs. DMSO at the same age). Abbreviations: Trt, Treatment.