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. Author manuscript; available in PMC: 2015 Aug 30.
Published in final edited form as: Int J Oncol. 2010 Jul;37(1):51–59. doi: 10.3892/ijo_00000652

Figure 2.

Figure 2

Dendrogram of 69 breast cancer specimens and three normal tissues analyzed by hierarchical clustering using intrinsic gene set (top), and pathological and IHC parameters of each tumor samples (bottom). The color scheme of dendrogram is identical to that of Fig. 1. LN, lymph node status of each tumor. Green squares are for positive lymph node metastasis and blanks for negative lymph node; ER/PR, dark blue squares are for tumors with both ER and PR positive by IHC, light blue squares for tumors positive for only one of ER or PR, and blanks for tumors negative for both ER and PR; NG, nuclear grade. Red squares are for grade 3 tumors and blanks for grade 1 or 2; P53 and Ki-67, red squares are for tumors with percentage of positively stained cells in IHC ≥50%, pink squares for ≥10% and <50%, and blanks for <10%; HER-2, red squares are for HER-2 score of 3+ by IHC, pink squares are for 2+, and blank for 1+ or 0. All the gray squares shown in this figures are for missing data of each variable.