Table 2.
Factors predicting the average air and bone conduction threshold deterioration at the 1- to 5-year follow-up after RT.
| Variables | N (= 182) | Air (dB) Mean ± SEM |
p value | Bone (dB) Mean ± SEM |
p value |
|---|---|---|---|---|---|
| Sex | |||||
| Female | 53 | 15.67 ± 3.02 | 0.556 | 9.05 ± 12.27 | 0.591 |
| Male | 129 | 17.64 ± 1.65 | 10.12 ± 12.05 | ||
| Radiation modality | |||||
| 2D-3D CRT | 75 | 24.00 ± 2.34 | 0.000 | 14.04 ± 1.54 | 0.000 |
| IMRT | 107 | 12.21 ± 1.71 | 6.85 ± 0.99 | ||
| Age (years) | |||||
| <50 | 89 | 18.73 ± 2.30 | 0.267 | 10.55 ± 1.38 | 0.421 |
| >50 | 93 | 15.47 ± 1.81 | 9.10 ± 1.15 | ||
| Treatment regimen | |||||
| RT alone | 89 | 19.93 ± 2.23 | 0.060 | 10.65 ± 1.23 | 0.359 |
| Chemoradiotherapy | 93 | 14.32 ± 1.86 | 9.58 ± 1.30 | ||
| Radiation dose | |||||
| <72 Gy | 35 | 10.24 ± 3.01 | 0.017 | 6.66 ± 1.65 | 0.026 |
| >72 Gy | 147 | 18.69 ± 1.63 | 10.26 ± 1.03 | ||
| Otitis media effusion | |||||
| No | 111 | 15.54 ± 1.81 | 0.019 | 8.09 ± 1.00 | 0.016 |
| Yes | 71 | 19.46 ± 2.43 | 12.50 ± 1.65 |
∗SEM = standard error of the mean; RT = radiotherapy; 2D-3D CRT = 2-dimensional-3-dimensional conformal radiotherapy; IMRT = intensity-modulated radiotherapy.