TABLE 3.

Calculation of 1-Year HCC Risk Using the ADRESS-HCC Model

Step 1: calculate ADRESS-HCC score = ([age] + [diabetes] + [race] + [etiology] + [sex] + [severity]) in which:

Age indicates the age in years × 0.0532

Diabetes indicates 0.2135 if present and 0 if absent

Race indicates 0.2058 if nonwhite or Hispanic or 0 if non-Hispanic white

Etiology indicates 0 if autoimmune, 0.3509 if alcohol/metabolic, and 1.246 if viral

Sex indicates 0.5114 if male and 0 if female

Severity indicates a CTP score (5–15) × 0.1170

Step 2: baseline hazard at 1 year: S0(t)=0.99986

Step 3: [100*(1-S0(t)*exp(ADRESS-HCCScore)]=1-year HCC risk (%)

Abbreviations: ADRESS, age, diabetes, race, etiology of cirrhosis, sex, and severity; CTP, Child-Turcotte-Pugh; HCC, hepatocellular carcinoma.