Table I. Various proteomic approaches in rheumatoid arthritis (RA) research.

DEPs, Differentially expressed proteins; Ref, references; 2DE, 2-dimensional gel electrophoresis; LC-MS, liquid chromatography-coupled tandem mass spectrometry; CRP, C-reactive protein; MALDI-TOF-MS, matrix-assisted laser desorption ionization mass spectrometry; COTL1, coactosin-like1; SELDI-TOF-MS, surface enhanced laser desorption/ionisation time-of-flight mass spectrometry; OA, osteoarthritis; PIMT, protein isoaspartyl methyltransferase; PIR, pirin iron-binding nuclear protein; Trx-1, thioredoxin 1; NGAL, neutrophil gelatinase-associated lipocalin; PBMCs, peripheral blood mononuclear cells; WB, western blot; GRP78/BiP, glucose-regulated protein precursor; ACPA, anti-citrullinated peptide/protein antibodies; TNFα, tumor necrosis factor-α; MSCs, mesenchymal stem cells; DEGs, differential expression genes; MRP-8, myeloid related protein-8; SpA, spondyloarthropathy.