Table 2.
The effects of Cordyceps militaris fruit body extract on liver antioxidant status in mice before and after swimming.
| Female | Male | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CTRL | CM (g/kg) | Pro (g/kg) | CTRL | CM (g/kg) | Pro (g/kg) | |||||
| 0.5 | 1.0 | 2.0 | 0.5 | 0.5 | 1.0 | 2.0 | 0.5 | |||
| Before swimming | ||||||||||
| MDA (nmol/mg prot) | 0.53 ± 0.18 | 0.40 ± 0.08 | 0.25 ± 0.07∗ | 0.27 ± 0.15∗ | 0.50 ± 0.23 | 0.50 ± 0.17 | 0.39 ± 0.10 | 0.31 ± 0.12 | 0.30 ± 0.11 | 0.51 ± 0.09 |
| ROS (FI/g prot) | 1988 ± 203 | 1728 ± 278 | 1645 ± 158∗ | 1488 ± 202∗∗ | 1702 ± 189 | 1836 ± 147 | 1680 ± 203 | 1687 ± 256 | 1598 ± 108∗ | 1806 ± 217 |
| SOD (U/mg prot) | 196 ± 55 | 197 ± 16 | 196 ± 7 | 194 ± 17 | 201 ± 18 | 199 ± 16 | 194 ± 20 | 180 ± 15 | 174 ± 9 | 199 ± 15 |
| GSH-Px (μmol/g prot) | 22 ± 7 | 24 ± 5 | 28 ± 7 | 29 ± 6∗ | 24 ± 5 | 24 ± 5 | 26 ± 4 | 29 ± 6 | 29 ± 3∗ | 26 ± 5 |
| After swimming | ||||||||||
| MDA (nmol/mg prot) | 0.49 ± 0.075 | 0.36 ± 0.099 | 0.39 ± 0.104 | 0.21 ± 0.034∗∗ | 0.54 ± 10.02 | 0.76 ± 0.151 | 0.35 ± 0.089∗∗ | 0.43 ± 0.132∗ | 0.32 ± 0.082∗∗ | 0.50 ± 0.18 |
| ROS (FI/g prot) | 2128 ± 287 | 1928 ± 387 | 1351 ± 127∗∗ | 1288 ± 122∗∗ | 1601 ± 265∗ | 2158 ± 333 | 1590 ± 165∗∗ | 1580 ± 336∗ | 1317 ± 108∗∗ | 1606 ± 323∗ |
| SOD (U/mg prot) | 216 ± 73 | 196 ± 15 | 214 ± 84 | 323 ± 41∗ | 364 ± 94∗ | 146 ± 36 | 152 ± 47 | 231 ± 66∗ | 302 ± 35∗∗ | 349 ± 60∗∗ |
| GSH-Px (μmol/g prot) | 37 ± 7 | 29 ± 7 | 31 ± 5 | 31 ± 10 | 46 ± 16 | 30 ± 5 | 34 ± 8 | 30 ± 3 | 30 ± 6 | 36 ± 8 |
Treatment with Cordyceps militaris fruit body extract (0.5 g/kg, 1.0 g/kg, and 2.0 g/kg) and Rhodiola rosea (0.5 g/kg) for 2 weeks; before and after 20 min swimming, the levels of MDA, ROS, and the activities of SOD and GSH-Px in liver in male and female mouse were detected. Values are expressed as mean ± S.D. (n = 6). ∗ P < 0.05 and ∗∗ P < 0.01 compared with control group.