Table 3.
The effects of Cordyceps militaris fruit body extract on skeletal muscle antioxidant status in mice before and after swimming.
| Female | Male | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CTRL | CM (g/kg) | Pro (g/kg) | CTRL | CM (g/kg) | Pro (g/kg) | |||||
| 0.5 | 1.0 | 2.0 | 0.5 | 0.5 | 1.0 | 2.0 | 0.5 | |||
| Before swimming | ||||||||||
| MDA (nmol/mg prot) | 0.78 ± 0.23 | 0.71 ± 0.19 | 0.77 ± 0.19 | 0.65 ± 0.20∗ | 0.73 ± 0.16 | 0.80 ± 0.25 | 0.75 ± 0.14 | 0.70 ± 0.19 | 0.69 ± 0.17 | 0.72 ± 0.16 |
| ROS (FI/g prot) | 15634 ± 1256 | 14569 ± 2012 | 15046 ± 2456 | 14569 ± 2178 | 14123 ± 1098 | 16023 ± 1891 | 15698 ± 2541 | 15036 ± 2013 | 15786 ± 1689 | 14563 ± 1048 |
| SOD (U/mg prot) | 113 ± 13 | 117 ± 19 | 1165 ± 13 | 115 ± 19 | 139 ± 30 | 117 ± 13 | 119 ± 27 | 117 ± 11 | 124 ± 11 | 157 ± 21∗ |
| GSH-Px (μmol/g prot) | 10 ± 2 | 11 ± 3 | 13 ± 2 | 12 ± 2 | 11 ± 4 | 9 ± 2 | 11 ± 2 | 11 ± 3 | 13 ± 1∗ | 13 ± 1∗ |
| After swimming | ||||||||||
| MDA (nmol/mg prot) | 1.13 ± 0.46 | 0.77 ± 0.30 | 0.76 ± 0.31 | 0.69 ± 0.25∗ | 0.72 ± 0.34 | 1.16 ± 0.45 | 1.07 ± 0.42 | 0.62 ± 0.18∗∗ | 0.89 ± 0.13 | 0.79 ± 0.17 |
| ROS (FI/g prot) | 22108 ± 2918 | 17812 ± 2954 | 16933 ± 3149 | 15381 ± 138∗ | 17885 ± 5084 | 23018 ± 1491 | 22846 ± 1496 | 18057 ± 2310∗ | 17038 ± 2119∗∗ | 17313 ± 3852 |
| SOD (U/mg prot) | 98 ± 10 | 100 ± 10 | 116 ± 22 | 128 ± 9∗∗ | 117 ± 5∗ | 101 ± 5 | 98 ± 14 | 100 ± 10 | 111 ± 8∗ | 120 ± 9∗∗ |
| GSH-Px (μmol/g prot) | 9 ± 2 | 13 ± 1∗ | 11 ± 3 | 14 ± 3∗∗ | 11 ± 2 | 9 ± 1 | 10 ± 1 | 11 ± 2∗ | 10 ± 2 | 11 ± 2∗ |
Treatment with Cordyceps militaris fruit body extract (0.5 g/kg, 1.0 g/kg, and 2.0 g/kg) and Rhodiola rosea (0.5 g/kg) for 2 weeks; before and after 20 min swimming, the levels of MDA, ROS, and the activities of SOD and GSH-Px in skeletal muscle in male and female mouse were detected. Values are expressed as mean ± S.D. (n = 6). ∗ P < 0.05 and ∗∗ P < 0.01 compared with control group.