Fig. 1. Schematic representation of the murine model of allergic rhinitis and treatment protocol. BALB/c mice were sensitized with ovalbumin (OVA) and 1 mg of aluminum hydroxide (Alum) on days 0, 7, and 14. All groups except control received intranasal OVA from 21 days to 24 days. In addition to sensitization and challenge, TSA+OVA mice were injected with TSA (1 mg/kg/day). TSA, trichostatin A.
